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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TDG All Species: 35.76
Human Site: T314 Identified Species: 87.41
UniProt: Q13569 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13569 NP_003202.3 410 46053 T314 D V Q E V Q Y T F D L Q L A Q
Chimpanzee Pan troglodytes XP_509324 541 60619 T445 D V Q E V Q Y T F D L Q L A Q
Rhesus Macaque Macaca mulatta XP_001096295 410 46108 T314 D V Q E V Q Y T F D L Q L A Q
Dog Lupus familis XP_532673 621 68331 T529 D V Q E V Q Y T F D L Q L A Q
Cat Felis silvestris
Mouse Mus musculus P56581 397 44071 T301 D V Q E V Q Y T F D L Q L A Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507661 567 62055 T472 E I Q E V Q Y T F N L Q L A R
Chicken Gallus gallus NP_990081 408 46080 T312 E V Q E V Q Y T F D L Q L A Q
Frog Xenopus laevis NP_001084290 440 49090 T348 E I Q E V Q Y T F D L Q L A Q
Zebra Danio Brachydanio rerio NP_001018587 441 49117 T342 E V E E V N Y T F D L G L A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392189 973 106396 Q493 E M R E R E H Q H Q Q Q H Q Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.9 97.3 59.9 N.A. 85.3 N.A. N.A. 60.6 78.7 62.5 55.5 N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: 100 74.3 99 61.6 N.A. 88.2 N.A. N.A. 64.5 84.1 74 67.8 N.A. N.A. 29.2 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 73.3 93.3 86.6 66.6 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 100 86.6 N.A. N.A. 53.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % D
% Glu: 50 0 10 100 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 10 0 0 0 10 0 0 % H
% Ile: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 90 0 90 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 80 0 0 80 0 10 0 10 10 90 0 10 80 % Q
% Arg: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % T
% Val: 0 70 0 0 90 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _