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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAPTM5 All Species: 5.45
Human Site: S131 Identified Species: 13.33
UniProt: Q13571 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13571 NP_006753.1 262 29937 S131 A S R S R A S S S K F P L M T
Chimpanzee Pan troglodytes XP_513264 461 50680 S330 A S R S R A S S S K F P L M T
Rhesus Macaque Macaca mulatta XP_001092380 400 44397 P269 A S R S R A S P S K F P L M T
Dog Lupus familis XP_544450 262 29654 P131 A S R S S R G P S K V P L M T
Cat Felis silvestris
Mouse Mus musculus Q61168 261 29583 S131 A R P R P G P S K V P L M T L
Rat Rattus norvegicus Q5U1W4 227 25385 A99 G A Y K Q H A A W I I P F F C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521798 373 40877 G191 A T A T R A R G R P K T P R V
Chicken Gallus gallus Q5ZML7 229 26256 R101 V Y G A I A H R V G W L I P F
Frog Xenopus laevis NP_001121245 225 25503 H97 T Y G A Y K Q H A A W I I P F
Zebra Danio Brachydanio rerio NP_999850 238 27236 R110 V Y G A I T N R D G W L I P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.1 59.2 85.1 N.A. 79 24.4 N.A. 41.8 24.4 27.1 20.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.6 62.2 90.8 N.A. 87 42.7 N.A. 52.8 45 42.7 40 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 13.3 6.6 N.A. 20 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 66.6 N.A. 20 33.3 N.A. 33.3 26.6 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 10 10 30 0 50 10 10 10 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 30 0 10 10 30 % F
% Gly: 10 0 30 0 0 10 10 10 0 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 0 0 0 0 10 10 10 30 0 0 % I
% Lys: 0 0 0 10 0 10 0 0 10 40 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 30 40 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 40 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 10 0 10 20 0 10 10 50 10 30 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 40 10 40 10 10 20 10 0 0 0 0 10 0 % R
% Ser: 0 40 0 40 10 0 30 30 40 0 0 0 0 0 0 % S
% Thr: 10 10 0 10 0 10 0 0 0 0 0 10 0 10 40 % T
% Val: 20 0 0 0 0 0 0 0 10 10 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 30 0 0 0 0 % W
% Tyr: 0 30 10 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _