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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPK1
All Species:
35.76
Human Site:
S127
Identified Species:
60.51
UniProt:
Q13572
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13572
NP_001136065.1
414
45621
S127
M
E
D
D
R
I
C
S
P
P
F
M
E
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094303
414
45602
S127
M
E
D
D
R
I
C
S
P
P
F
M
E
L
T
Dog
Lupus familis
XP_547713
419
45752
S127
M
K
D
D
R
I
C
S
P
P
F
M
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYN3
419
46127
S127
M
K
D
D
R
I
C
S
P
P
F
M
E
L
T
Rat
Rattus norvegicus
XP_576090
421
46186
S127
M
K
D
D
R
I
C
S
P
P
F
M
E
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510760
433
47489
S153
M
K
D
E
R
I
C
S
P
P
F
M
E
L
T
Chicken
Gallus gallus
Q5F480
407
45297
S127
M
Q
D
E
R
I
C
S
P
P
F
M
E
L
T
Frog
Xenopus laevis
Q7SY78
396
44199
S127
M
Q
D
E
R
I
C
S
P
P
F
M
E
L
M
Zebra Danio
Brachydanio rerio
Q7ZU91
396
44174
S127
M
E
D
D
R
I
C
S
P
P
F
M
V
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624117
325
37462
T58
H
V
F
I
Y
K
M
T
D
K
L
A
H
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195347
378
41846
Q111
M
Q
L
L
R
K
A
Q
V
G
F
P
L
V
C
Poplar Tree
Populus trichocarpa
XP_002306515
319
35887
L52
Q
G
P
F
D
I
V
L
H
K
L
T
G
K
E
Maize
Zea mays
Q84Y01
342
37294
D74
L
I
H
K
L
Y
G
D
D
W
R
A
Q
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SBA5
319
36201
G52
T
K
S
L
L
E
Q
G
K
L
D
C
I
I
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
93.5
N.A.
93
92.8
N.A.
74.8
83
74.6
63.7
N.A.
N.A.
30.9
N.A.
32.8
Protein Similarity:
100
N.A.
98.3
95.2
N.A.
95.6
95.4
N.A.
83.8
91.3
85.2
78.2
N.A.
N.A.
52.4
N.A.
51.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
80
86.6
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
26
21
N.A.
24.1
N.A.
N.A.
Protein Similarity:
41.5
40.1
N.A.
42.5
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
65
0
0
0
0
8
0
0
8
% C
% Asp:
0
0
65
43
8
0
0
8
15
0
8
0
0
0
0
% D
% Glu:
0
22
0
22
0
8
0
0
0
0
0
0
58
0
15
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
72
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
8
0
8
0
0
8
0
0
% G
% His:
8
0
8
0
0
0
0
0
8
0
0
0
8
0
8
% H
% Ile:
0
8
0
8
0
72
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
36
0
8
0
15
0
0
8
15
0
0
0
8
8
% K
% Leu:
8
0
8
15
15
0
0
8
0
8
15
0
8
72
0
% L
% Met:
72
0
0
0
0
0
8
0
0
0
0
65
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
65
65
0
8
0
0
0
% P
% Gln:
8
22
0
0
0
0
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
72
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
65
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
50
% T
% Val:
0
8
0
0
0
0
8
0
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _