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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPK1 All Species: 20
Human Site: S232 Identified Species: 33.85
UniProt: Q13572 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13572 NP_001136065.1 414 45621 S232 R E S I F F N S H N V S K P E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094303 414 45602 S232 R E S I F F N S H N V S K P E
Dog Lupus familis XP_547713 419 45752 S232 R E S I F F N S H N V S K P E
Cat Felis silvestris
Mouse Mus musculus Q8BYN3 419 46127 S232 R E S I F F N S H N V S K P E
Rat Rattus norvegicus XP_576090 421 46186 S232 R E S I F F N S H N V S K P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510760 433 47489 E252 S A G T S D R E S I F F N S H
Chicken Gallus gallus Q5F480 407 45297 E226 S A G I S D R E S I F F N S H
Frog Xenopus laevis Q7SY78 396 44199 K216 V V E R P S L K N F S L G A S
Zebra Danio Brachydanio rerio Q7ZU91 396 44174 I215 S V V Q R P S I R N F P S G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624117 325 37462 F146 L K M A G I K F P F L C K P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195347 378 41846 S199 F F D S H D V S K F N S T S F
Poplar Tree Populus trichocarpa XP_002306515 319 35887 P140 M L P I V A K P L V A D G S A
Maize Zea mays Q84Y01 342 37294 T162 K P L V A D G T A K S H K M S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SBA5 319 36201 F140 G A L G E L K F P V I A K P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 93.5 N.A. 93 92.8 N.A. 74.8 83 74.6 63.7 N.A. N.A. 30.9 N.A. 32.8
Protein Similarity: 100 N.A. 98.3 95.2 N.A. 95.6 95.4 N.A. 83.8 91.3 85.2 78.2 N.A. N.A. 52.4 N.A. 51.2
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 6.6 0 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 6.6 6.6 13.3 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: 26 21 N.A. 24.1 N.A. N.A.
Protein Similarity: 41.5 40.1 N.A. 42.5 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 6.6 26.6 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 8 8 8 0 0 8 0 8 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 0 29 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 36 8 0 8 0 0 15 0 0 0 0 0 0 36 % E
% Phe: 8 8 0 0 36 36 0 15 0 22 22 15 0 0 8 % F
% Gly: 8 0 15 8 8 0 8 0 0 0 0 0 15 8 0 % G
% His: 0 0 0 0 8 0 0 0 36 0 0 8 0 0 15 % H
% Ile: 0 0 0 50 0 8 0 8 0 15 8 0 0 0 0 % I
% Lys: 8 8 0 0 0 0 22 8 8 8 0 0 58 0 0 % K
% Leu: 8 8 15 0 0 8 8 0 8 0 8 8 0 0 15 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 36 0 8 43 8 0 15 0 0 % N
% Pro: 0 8 8 0 8 8 0 8 15 0 0 8 0 50 8 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 36 0 0 8 8 0 15 0 8 0 0 0 0 0 0 % R
% Ser: 22 0 36 8 15 8 8 43 15 0 15 43 8 29 15 % S
% Thr: 0 0 0 8 0 0 0 8 0 0 0 0 8 0 0 % T
% Val: 8 15 8 8 8 0 8 0 0 15 36 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _