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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPK1
All Species:
18.48
Human Site:
S240
Identified Species:
31.28
UniProt:
Q13572
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13572
NP_001136065.1
414
45621
S240
H
N
V
S
K
P
E
S
S
S
V
L
T
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094303
414
45602
S240
H
N
V
S
K
P
E
S
S
S
V
L
T
E
L
Dog
Lupus familis
XP_547713
419
45752
S240
H
N
V
S
K
P
E
S
S
S
V
L
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYN3
419
46127
S240
H
N
V
S
K
P
E
S
S
S
V
L
T
E
L
Rat
Rattus norvegicus
XP_576090
421
46186
S240
H
N
V
S
K
P
E
S
S
S
V
L
T
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510760
433
47489
N260
S
I
F
F
N
S
H
N
V
S
K
P
E
S
S
Chicken
Gallus gallus
Q5F480
407
45297
N234
S
I
F
F
N
S
H
N
V
S
K
P
E
S
S
Frog
Xenopus laevis
Q7SY78
396
44199
D224
N
F
S
L
G
A
S
D
R
A
S
I
F
F
N
Zebra Danio
Brachydanio rerio
Q7ZU91
396
44174
T223
R
N
F
P
S
G
P
T
D
R
R
A
I
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624117
325
37462
V154
P
F
L
C
K
P
L
V
A
Q
G
S
N
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195347
378
41846
L207
K
F
N
S
T
S
F
L
N
E
L
D
E
T
D
Poplar Tree
Populus trichocarpa
XP_002306515
319
35887
K148
L
V
A
D
G
S
A
K
S
H
E
L
S
L
A
Maize
Zea mays
Q84Y01
342
37294
L170
A
K
S
H
K
M
S
L
V
Y
H
R
E
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SBA5
319
36201
D148
P
V
I
A
K
P
L
D
A
D
G
S
A
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
93.5
N.A.
93
92.8
N.A.
74.8
83
74.6
63.7
N.A.
N.A.
30.9
N.A.
32.8
Protein Similarity:
100
N.A.
98.3
95.2
N.A.
95.6
95.4
N.A.
83.8
91.3
85.2
78.2
N.A.
N.A.
52.4
N.A.
51.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
13.3
13.3
20
13.3
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
26
21
N.A.
24.1
N.A.
N.A.
Protein Similarity:
41.5
40.1
N.A.
42.5
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
8
0
15
8
0
8
8
8
15
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
15
8
8
0
8
0
8
8
% D
% Glu:
0
0
0
0
0
0
36
0
0
8
8
0
29
29
0
% E
% Phe:
0
22
22
15
0
0
8
0
0
0
0
0
8
8
8
% F
% Gly:
0
0
0
0
15
8
0
0
0
0
15
0
0
8
0
% G
% His:
36
0
0
8
0
0
15
0
0
8
8
0
0
0
0
% H
% Ile:
0
15
8
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
8
8
0
0
58
0
0
8
0
0
15
0
0
8
0
% K
% Leu:
8
0
8
8
0
0
15
15
0
0
8
43
0
8
43
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
43
8
0
15
0
0
15
8
0
0
0
8
0
8
% N
% Pro:
15
0
0
8
0
50
8
0
0
0
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
8
8
8
0
0
0
% R
% Ser:
15
0
15
43
8
29
15
36
43
50
8
15
8
22
22
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
36
8
0
% T
% Val:
0
15
36
0
0
0
0
8
22
0
36
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _