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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPK1 All Species: 20
Human Site: S242 Identified Species: 33.85
UniProt: Q13572 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13572 NP_001136065.1 414 45621 S242 V S K P E S S S V L T E L D K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094303 414 45602 S242 V S K P E S S S V L T E L D K
Dog Lupus familis XP_547713 419 45752 S242 V S K P E S S S V L T A L D K
Cat Felis silvestris
Mouse Mus musculus Q8BYN3 419 46127 S242 V S K P E S S S V L T E L D K
Rat Rattus norvegicus XP_576090 421 46186 S242 V S K P E S S S V L T E L D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510760 433 47489 S262 F F N S H N V S K P E S S S V
Chicken Gallus gallus Q5F480 407 45297 S236 F F N S H N V S K P E S S S V
Frog Xenopus laevis Q7SY78 396 44199 A226 S L G A S D R A S I F F N S H
Zebra Danio Brachydanio rerio Q7ZU91 396 44174 R225 F P S G P T D R R A I S F N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624117 325 37462 Q156 L C K P L V A Q G S N D A H K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195347 378 41846 E209 N S T S F L N E L D E T D A A
Poplar Tree Populus trichocarpa XP_002306515 319 35887 H150 A D G S A K S H E L S L A Y D
Maize Zea mays Q84Y01 342 37294 Y172 S H K M S L V Y H R E G L G K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SBA5 319 36201 D150 I A K P L D A D G S A K S H K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 93.5 N.A. 93 92.8 N.A. 74.8 83 74.6 63.7 N.A. N.A. 30.9 N.A. 32.8
Protein Similarity: 100 N.A. 98.3 95.2 N.A. 95.6 95.4 N.A. 83.8 91.3 85.2 78.2 N.A. N.A. 52.4 N.A. 51.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 6.6 6.6 0 0 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 13.3 13.3 13.3 13.3 N.A. N.A. 40 N.A. 20
Percent
Protein Identity: 26 21 N.A. 24.1 N.A. N.A.
Protein Similarity: 41.5 40.1 N.A. 42.5 N.A. N.A.
P-Site Identity: 13.3 20 N.A. 20 N.A. N.A.
P-Site Similarity: 20 20 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 8 0 15 8 0 8 8 8 15 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 15 8 8 0 8 0 8 8 36 8 % D
% Glu: 0 0 0 0 36 0 0 8 8 0 29 29 0 0 0 % E
% Phe: 22 15 0 0 8 0 0 0 0 0 8 8 8 0 0 % F
% Gly: 0 0 15 8 0 0 0 0 15 0 0 8 0 8 0 % G
% His: 0 8 0 0 15 0 0 8 8 0 0 0 0 15 8 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 58 0 0 8 0 0 15 0 0 8 0 0 58 % K
% Leu: 8 8 0 0 15 15 0 0 8 43 0 8 43 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 15 0 0 15 8 0 0 0 8 0 8 8 0 % N
% Pro: 0 8 0 50 8 0 0 0 0 15 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 8 8 0 0 0 0 0 % R
% Ser: 15 43 8 29 15 36 43 50 8 15 8 22 22 22 8 % S
% Thr: 0 0 8 0 0 8 0 0 0 0 36 8 0 0 0 % T
% Val: 36 0 0 0 0 8 22 0 36 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _