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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPK1
All Species:
33.03
Human Site:
T141
Identified Species:
55.9
UniProt:
Q13572
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13572
NP_001136065.1
414
45621
T141
T
S
L
C
G
D
D
T
M
R
L
L
E
K
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094303
414
45602
T141
T
S
L
C
G
D
D
T
M
Q
L
L
E
K
N
Dog
Lupus familis
XP_547713
419
45752
T141
T
S
L
S
G
D
D
T
M
R
L
L
E
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYN3
419
46127
T141
T
S
L
C
G
E
D
T
M
R
L
L
E
Q
N
Rat
Rattus norvegicus
XP_576090
421
46186
T141
T
S
L
C
G
D
D
T
M
R
L
L
E
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510760
433
47489
T167
T
S
L
C
G
E
D
T
M
Q
L
L
E
K
N
Chicken
Gallus gallus
Q5F480
407
45297
T141
T
S
A
C
G
E
D
T
L
Q
L
I
E
K
N
Frog
Xenopus laevis
Q7SY78
396
44199
T141
M
A
E
C
D
E
D
T
L
K
I
L
E
K
N
Zebra Danio
Brachydanio rerio
Q7ZU91
396
44174
T141
K
T
E
C
G
F
E
T
L
E
Q
L
H
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624117
325
37462
K72
E
Y
G
D
Q
N
A
K
A
I
I
S
K
M
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195347
378
41846
G125
C
K
P
S
Q
A
H
G
S
L
I
S
H
K
M
Poplar Tree
Populus trichocarpa
XP_002306515
319
35887
D66
E
W
R
Q
I
L
E
D
Y
R
R
T
H
P
E
Maize
Zea mays
Q84Y01
342
37294
P88
V
A
F
A
A
R
H
P
A
V
P
I
V
D
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SBA5
319
36201
W66
H
K
L
Y
D
V
Y
W
K
E
N
L
H
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
93.5
N.A.
93
92.8
N.A.
74.8
83
74.6
63.7
N.A.
N.A.
30.9
N.A.
32.8
Protein Similarity:
100
N.A.
98.3
95.2
N.A.
95.6
95.4
N.A.
83.8
91.3
85.2
78.2
N.A.
N.A.
52.4
N.A.
51.2
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
86.6
93.3
N.A.
86.6
66.6
46.6
33.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
93.3
80
60
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
26
21
N.A.
24.1
N.A.
N.A.
Protein Similarity:
41.5
40.1
N.A.
42.5
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
8
8
8
8
0
15
0
0
0
0
0
0
% A
% Cys:
8
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
29
58
8
0
0
0
0
0
8
0
% D
% Glu:
15
0
15
0
0
29
15
0
0
15
0
0
58
8
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
58
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
15
0
0
0
0
0
29
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
22
15
0
0
0
% I
% Lys:
8
15
0
0
0
0
0
8
8
8
0
0
8
50
8
% K
% Leu:
0
0
50
0
0
8
0
0
22
8
50
65
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
43
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
58
% N
% Pro:
0
0
8
0
0
0
0
8
0
0
8
0
0
8
8
% P
% Gln:
0
0
0
8
15
0
0
0
0
22
8
0
0
22
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
36
8
0
0
0
0
% R
% Ser:
0
50
0
15
0
0
0
0
8
0
0
15
0
0
0
% S
% Thr:
50
8
0
0
0
0
0
65
0
0
0
8
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _