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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPK1 All Species: 20.91
Human Site: T354 Identified Species: 35.38
UniProt: Q13572 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13572 NP_001136065.1 414 45621 T354 G G L V G E R T C S A S P G C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094303 414 45602 T354 G G L T G E R T C S A S P G C
Dog Lupus familis XP_547713 419 45752 T354 G S L A G E R T C S A G P G C
Cat Felis silvestris
Mouse Mus musculus Q8BYN3 419 46127 T354 G S L A G E R T C S A S P G C
Rat Rattus norvegicus XP_576090 421 46186 T354 G S L A G E R T C S A S P G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510760 433 47489 T374 G G L T G D R T C G P G P G C
Chicken Gallus gallus Q5F480 407 45297 I348 G G I M D E R I C C A S T G C
Frog Xenopus laevis Q7SY78 396 44199 S338 S V E Q T G S S L G E R L C C
Zebra Danio Brachydanio rerio Q7ZU91 396 44174 G337 C G H L R V N G T A Q S Q T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624117 325 37462 E268 K I V K R V T E L F G L L L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195347 378 41846 S321 L T P I L Q D S R D S R E E V
Poplar Tree Populus trichocarpa XP_002306515 319 35887 D262 G L R L F N L D I I R E H G T
Maize Zea mays Q84Y01 342 37294 I284 Q L F N F D M I R D V R A G D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SBA5 319 36201 R262 T D L A K A M R E S M G L N L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 93.5 N.A. 93 92.8 N.A. 74.8 83 74.6 63.7 N.A. N.A. 30.9 N.A. 32.8
Protein Similarity: 100 N.A. 98.3 95.2 N.A. 95.6 95.4 N.A. 83.8 91.3 85.2 78.2 N.A. N.A. 52.4 N.A. 51.2
P-Site Identity: 100 N.A. 93.3 80 N.A. 86.6 86.6 N.A. 66.6 60 6.6 13.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 N.A. 93.3 80 N.A. 86.6 86.6 N.A. 73.3 73.3 13.3 26.6 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: 26 21 N.A. 24.1 N.A. N.A.
Protein Similarity: 41.5 40.1 N.A. 42.5 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 29 0 8 0 0 0 8 43 0 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 50 8 0 0 0 8 58 % C
% Asp: 0 8 0 0 8 15 8 8 0 15 0 0 0 0 8 % D
% Glu: 0 0 8 0 0 43 0 8 8 0 8 8 8 8 0 % E
% Phe: 0 0 8 0 15 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 58 36 0 0 43 8 0 8 0 15 8 22 0 65 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 8 8 0 0 0 15 8 8 0 0 0 0 0 % I
% Lys: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 15 50 15 8 0 8 0 15 0 0 8 22 8 8 % L
% Met: 0 0 0 8 0 0 15 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 8 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 8 0 43 0 0 % P
% Gln: 8 0 0 8 0 8 0 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 8 0 15 0 50 8 15 0 8 22 0 0 0 % R
% Ser: 8 22 0 0 0 0 8 15 0 43 8 43 0 0 0 % S
% Thr: 8 8 0 15 8 0 8 43 8 0 0 0 8 8 8 % T
% Val: 0 8 8 8 0 15 0 0 0 0 8 0 0 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _