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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPK1 All Species: 19.09
Human Site: Y302 Identified Species: 32.31
UniProt: Q13572 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13572 NP_001136065.1 414 45621 Y302 D I N A F P G Y E G V S E F F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094303 414 45602 Y302 D I N A F P G Y E G V S E F F
Dog Lupus familis XP_547713 419 45752 Y302 D I N A F P G Y E G V S E F F
Cat Felis silvestris
Mouse Mus musculus Q8BYN3 419 46127 Y302 D V N A F P G Y E G V S E F F
Rat Rattus norvegicus XP_576090 421 46186 Y302 D V N A F P G Y E G V S E F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510760 433 47489 V322 G Q H A V I D V N A F P G Y E
Chicken Gallus gallus Q5F480 407 45297 I296 G Q H A V I D I N A F P G Y E
Frog Xenopus laevis Q7SY78 396 44199 N286 G I D I I I N N K T G Q H A V
Zebra Danio Brachydanio rerio Q7ZU91 396 44174 N285 F G I D I I I N N Q T G Q H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624117 325 37462 K216 S F K N F Y E K D C T A L N T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195347 378 41846 G269 N A F P G Y D G V P D F M R V
Poplar Tree Populus trichocarpa XP_002306515 319 35887 A210 K R E L S N I A G V F R F P R
Maize Zea mays Q84Y01 342 37294 S232 A Q G S V S F S Q V S N L P T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SBA5 319 36201 E210 S L P D I S E E K I G T S K G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 93.5 N.A. 93 92.8 N.A. 74.8 83 74.6 63.7 N.A. N.A. 30.9 N.A. 32.8
Protein Similarity: 100 N.A. 98.3 95.2 N.A. 95.6 95.4 N.A. 83.8 91.3 85.2 78.2 N.A. N.A. 52.4 N.A. 51.2
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 6.6 6.6 6.6 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 20 20 20 6.6 N.A. N.A. 20 N.A. 6.6
Percent
Protein Identity: 26 21 N.A. 24.1 N.A. N.A.
Protein Similarity: 41.5 40.1 N.A. 42.5 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 0 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 50 0 0 0 8 0 15 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 36 0 8 15 0 0 22 0 8 0 8 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 15 8 36 0 0 0 36 0 15 % E
% Phe: 8 8 8 0 43 0 8 0 0 0 22 8 8 36 36 % F
% Gly: 22 8 8 0 8 0 36 8 8 36 15 8 15 0 8 % G
% His: 0 0 15 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 29 8 8 22 29 15 8 0 8 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 0 8 15 0 0 0 0 8 0 % K
% Leu: 0 8 0 8 0 0 0 0 0 0 0 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 36 8 0 8 8 15 22 0 0 8 0 8 0 % N
% Pro: 0 0 8 8 0 36 0 0 0 8 0 15 0 15 0 % P
% Gln: 0 22 0 0 0 0 0 0 8 8 0 8 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 8 0 8 8 % R
% Ser: 15 0 0 8 8 15 0 8 0 0 8 36 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 15 8 0 0 15 % T
% Val: 0 15 0 0 22 0 0 8 8 15 36 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 36 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _