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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKZ
All Species:
10.3
Human Site:
S344
Identified Species:
17.44
UniProt:
Q13574
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13574
NP_001099010.1
1117
124128
S344
I
N
F
R
C
K
P
S
F
R
E
S
G
S
R
Chimpanzee
Pan troglodytes
XP_508395
1117
124129
S344
I
N
F
R
C
K
P
S
F
R
E
S
G
S
R
Rhesus Macaque
Macaca mulatta
XP_001102461
1084
120447
V326
N
V
R
E
P
T
F
V
R
H
H
W
V
H
R
Dog
Lupus familis
XP_540755
766
85714
E85
G
A
L
C
S
E
P
E
R
Q
I
R
S
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
R248
I
P
P
T
W
I
L
R
A
R
R
P
Q
N
T
Rat
Rattus norvegicus
O08560
929
103991
R248
I
P
P
T
W
I
L
R
A
R
R
P
Q
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
F274
G
T
K
V
L
Q
M
F
M
W
F
L
N
P
R
Chicken
Gallus gallus
NP_001026363
953
106222
T272
S
S
K
K
K
K
R
T
S
F
K
R
K
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
A343
R
K
S
S
K
K
G
A
E
E
A
R
W
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
T644
S
T
L
A
C
K
P
T
Y
R
D
V
G
I
R
Honey Bee
Apis mellifera
XP_396522
837
92900
K156
T
S
S
R
K
K
S
K
D
K
E
K
E
Q
D
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
C256
R
S
G
E
K
R
R
C
A
A
C
H
I
V
A
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
T134
A
E
K
E
I
R
T
T
V
D
W
S
K
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
A47
I
L
T
I
A
Y
T
A
F
Q
W
R
R
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.3
65.1
N.A.
78.2
79.3
N.A.
54.7
67.8
N.A.
60.4
N.A.
31.9
31.2
31.6
43.1
Protein Similarity:
100
99.8
91.2
66.6
N.A.
80.5
80.5
N.A.
65.8
74.8
N.A.
70.6
N.A.
46.1
46.2
46.3
55
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
13.3
N.A.
6.6
13.3
N.A.
6.6
N.A.
40
20
0
6.6
P-Site Similarity:
100
100
6.6
26.6
N.A.
20
20
N.A.
13.3
40
N.A.
13.3
N.A.
60
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
0
0
15
22
8
8
0
0
0
8
% A
% Cys:
0
0
0
8
22
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% D
% Glu:
0
8
0
22
0
8
0
8
8
8
22
0
8
0
0
% E
% Phe:
0
0
15
0
0
0
8
8
22
8
8
0
0
0
0
% F
% Gly:
15
0
8
0
0
0
8
0
0
0
0
0
22
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
0
% H
% Ile:
36
0
0
8
8
15
0
0
0
0
8
0
8
8
8
% I
% Lys:
0
8
22
8
29
43
0
8
0
8
8
8
15
8
0
% K
% Leu:
0
8
15
0
8
0
15
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
8
15
0
0
0
0
0
0
0
0
0
0
8
22
0
% N
% Pro:
0
15
15
0
8
0
29
0
0
0
0
15
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
15
0
0
15
8
0
% Q
% Arg:
15
0
8
22
0
15
15
15
15
36
15
29
8
0
36
% R
% Ser:
15
22
15
8
8
0
8
15
8
0
0
22
8
22
8
% S
% Thr:
8
15
8
15
0
8
15
22
0
0
0
0
0
15
15
% T
% Val:
0
8
0
8
0
0
0
8
8
0
0
8
8
8
8
% V
% Trp:
0
0
0
0
15
0
0
0
0
8
15
8
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _