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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKZ All Species: 6.67
Human Site: T140 Identified Species: 11.28
UniProt: Q13574 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13574 NP_001099010.1 1117 124128 T140 A I Q P G T K T P G P P P P R
Chimpanzee Pan troglodytes XP_508395 1117 124129 T140 A I Q P G T K T P G P P P P R
Rhesus Macaque Macaca mulatta XP_001102461 1084 120447 S129 G S S R R R S S T V P P S C N
Dog Lupus familis XP_540755 766 85714
Cat Felis silvestris
Mouse Mus musculus Q80UP3 929 104029 F51 R F P G L R L F G H R K A I T
Rat Rattus norvegicus O08560 929 103991 F51 R F P G L R L F G H R K A I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513139 955 107141 V77 L G E E S C Q V K F A K S A L
Chicken Gallus gallus NP_001026363 953 106222 Q75 S L Q H M V A Q P N P V P A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922445 1086 121319 W143 A V Y G E H I W F E T N V S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09103 1457 160124 T331 G S P H F G N T L L P P Q P T
Honey Bee Apis mellifera XP_396522 837 92900
Nematode Worm Caenorhab. elegans Q10024 937 105180 A59 S K Q Q L S G A A D G M D G S
Sea Urchin Strong. purpuratus XP_796061 815 92455
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.3 65.1 N.A. 78.2 79.3 N.A. 54.7 67.8 N.A. 60.4 N.A. 31.9 31.2 31.6 43.1
Protein Similarity: 100 99.8 91.2 66.6 N.A. 80.5 80.5 N.A. 65.8 74.8 N.A. 70.6 N.A. 46.1 46.2 46.3 55
P-Site Identity: 100 100 13.3 0 N.A. 0 0 N.A. 0 26.6 N.A. 6.6 N.A. 26.6 0 6.6 0
P-Site Similarity: 100 100 20 0 N.A. 0 0 N.A. 13.3 40 N.A. 13.3 N.A. 26.6 0 20 0
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 0 0 8 8 8 0 8 0 15 15 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 0 0 8 8 8 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 15 0 0 8 0 0 15 8 8 0 0 0 0 0 % F
% Gly: 15 8 0 22 15 8 8 0 15 15 8 0 0 8 8 % G
% His: 0 0 0 15 0 8 0 0 0 15 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 8 0 0 0 0 0 0 15 0 % I
% Lys: 0 8 0 0 0 0 15 0 8 0 0 22 0 0 0 % K
% Leu: 8 8 0 0 22 0 15 0 8 8 0 0 0 0 15 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 8 0 0 8 % N
% Pro: 0 0 22 15 0 0 0 0 22 0 36 29 22 22 0 % P
% Gln: 0 0 29 8 0 0 8 8 0 0 0 0 8 0 0 % Q
% Arg: 15 0 0 8 8 22 0 0 0 0 15 0 0 0 15 % R
% Ser: 15 15 8 0 8 8 8 8 0 0 0 0 15 8 8 % S
% Thr: 0 0 0 0 0 15 0 22 8 0 8 0 0 0 22 % T
% Val: 0 8 0 0 0 8 0 8 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _