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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKZ All Species: 11.52
Human Site: T628 Identified Species: 19.49
UniProt: Q13574 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13574 NP_001099010.1 1117 124128 T628 E D R D E G A T D R L P L D V
Chimpanzee Pan troglodytes XP_508395 1117 124129 T628 E D R D E G A T D R L P L D V
Rhesus Macaque Macaca mulatta XP_001102461 1084 120447 T595 E D R D E G A T D R L P L D V
Dog Lupus familis XP_540755 766 85714 V331 W Y L N P R Q V F D L S Q G G
Cat Felis silvestris
Mouse Mus musculus Q80UP3 929 104029 L494 G T A F S D F L M G S S K D L
Rat Rattus norvegicus O08560 929 103991 L494 G T A F S D F L M G S S K D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513139 955 107141 G520 D G Y I E V I G F T M A S L A
Chicken Gallus gallus NP_001026363 953 106222 G518 H V K L V C D G V D L T P K I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922445 1086 121319 Q591 K V Q D L K L Q C L V F L N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09103 1457 160124 K957 D D H V D R S K P N V P L N V
Honey Bee Apis mellifera XP_396522 837 92900 T402 D C D G Q D L T P K L K E H R
Nematode Worm Caenorhab. elegans Q10024 937 105180 I502 P A Y P P M A I M P L G T G N
Sea Urchin Strong. purpuratus XP_796061 815 92455 S380 G T V G W I L S E I D K L K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 P293 E S T A D T G P T V N G A H A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.3 65.1 N.A. 78.2 79.3 N.A. 54.7 67.8 N.A. 60.4 N.A. 31.9 31.2 31.6 43.1
Protein Similarity: 100 99.8 91.2 66.6 N.A. 80.5 80.5 N.A. 65.8 74.8 N.A. 70.6 N.A. 46.1 46.2 46.3 55
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 N.A. 13.3 N.A. 26.6 13.3 13.3 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 20 20 N.A. 46.6 N.A. 60 33.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 8 0 0 29 0 0 0 0 8 8 0 15 % A
% Cys: 0 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 22 29 8 29 15 22 8 0 22 15 8 0 0 36 0 % D
% Glu: 29 0 0 0 29 0 0 0 8 0 0 0 8 0 0 % E
% Phe: 0 0 0 15 0 0 15 0 15 0 0 8 0 0 8 % F
% Gly: 22 8 0 15 0 22 8 15 0 15 0 15 0 15 8 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 8 0 8 8 8 0 8 0 0 0 0 15 % I
% Lys: 8 0 8 0 0 8 0 8 0 8 0 15 15 15 0 % K
% Leu: 0 0 8 8 8 0 22 15 0 8 50 0 43 8 15 % L
% Met: 0 0 0 0 0 8 0 0 22 0 8 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 8 8 0 0 15 8 % N
% Pro: 8 0 0 8 15 0 0 8 15 8 0 29 8 0 0 % P
% Gln: 0 0 8 0 8 0 8 8 0 0 0 0 8 0 0 % Q
% Arg: 0 0 22 0 0 15 0 0 0 22 0 0 0 0 8 % R
% Ser: 0 8 0 0 15 0 8 8 0 0 15 22 8 0 0 % S
% Thr: 0 22 8 0 0 8 0 29 8 8 0 8 8 0 0 % T
% Val: 0 15 8 8 8 8 0 8 8 8 15 0 0 0 29 % V
% Trp: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 15 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _