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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNASE1L3
All Species:
24.24
Human Site:
S161
Identified Species:
59.26
UniProt:
Q13609
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13609
NP_004935.1
305
35504
S161
L
H
T
T
P
E
T
S
V
K
E
I
D
E
L
Chimpanzee
Pan troglodytes
XP_001174037
305
35527
S161
L
H
T
T
P
E
T
S
V
K
E
I
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001097104
305
35444
S161
L
H
T
T
P
E
T
S
V
K
E
I
D
E
L
Dog
Lupus familis
XP_533780
304
35072
S161
L
H
T
T
P
E
A
S
V
K
E
I
D
E
L
Cat
Felis silvestris
Mouse
Mus musculus
O55070
310
35741
S166
L
H
T
T
P
E
T
S
V
K
E
I
D
E
L
Rat
Rattus norvegicus
O89107
310
35689
S166
L
H
T
T
P
E
T
S
V
K
E
I
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506333
315
35674
T178
V
M
F
S
S
P
S
T
E
V
K
E
F
V
I
Chicken
Gallus gallus
Q9YGI5
282
31382
D146
S
S
P
T
T
Q
L
D
E
F
V
I
V
P
L
Frog
Xenopus laevis
NP_001079750
295
34205
A158
Q
H
T
T
P
E
A
A
V
R
E
I
D
E
L
Zebra Danio
Brachydanio rerio
NP_998318
317
36424
A163
Q
H
T
T
P
S
N
A
T
K
E
I
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.7
83.6
N.A.
80.3
82.5
N.A.
47.2
41.9
59.3
47.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.6
89.8
N.A.
90
90.9
N.A.
61.2
60.6
74.4
62.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
20
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
40
26.6
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
80
0
0
% D
% Glu:
0
0
0
0
0
70
0
0
20
0
80
10
0
80
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
70
10
0
0
0
0
% K
% Leu:
60
0
0
0
0
0
10
0
0
0
0
0
0
0
90
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
80
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
20
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
10
0
10
10
10
10
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
80
90
10
0
50
10
10
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
70
10
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _