KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP1
All Species:
16.36
Human Site:
S249
Identified Species:
32.73
UniProt:
Q13610
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13610
NP_008993.1
501
55828
S249
K
K
K
K
G
K
K
S
S
S
A
E
G
H
T
Chimpanzee
Pan troglodytes
XP_001162437
430
48207
V178
Q
E
E
D
S
F
Y
V
H
H
D
I
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001093636
372
41113
Y121
S
L
L
G
L
T
V
Y
G
S
N
D
Q
D
P
Dog
Lupus familis
XP_531756
500
55840
S248
K
K
K
K
G
K
K
S
S
S
A
E
G
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99LL5
501
55568
S248
K
K
K
K
G
K
K
S
S
S
A
E
G
H
T
Rat
Rattus norvegicus
XP_343187
500
55792
S248
K
K
K
K
G
K
K
S
S
S
A
E
G
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508747
534
59511
V278
K
K
K
K
G
K
K
V
S
T
P
E
G
H
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084632
504
56148
E253
G
K
K
G
A
S
S
E
E
T
Q
E
G
H
S
Zebra Danio
Brachydanio rerio
NP_956586
490
54644
K237
S
L
G
S
K
K
E
K
K
K
K
K
K
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396674
460
52260
K209
P
I
Y
K
L
G
C
K
A
N
K
K
K
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788925
939
103869
T649
K
K
S
K
Q
K
P
T
A
P
S
L
N
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21304
576
63785
N295
A
V
L
S
M
A
H
N
K
Y
F
R
S
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
73.2
98.8
N.A.
89.8
90.2
N.A.
75.6
N.A.
69.8
70
N.A.
N.A.
38.9
N.A.
29.7
Protein Similarity:
100
85.8
73.6
99.1
N.A.
94
94.8
N.A.
84
N.A.
83.9
84.2
N.A.
N.A.
58.6
N.A.
40.1
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
80
N.A.
33.3
6.6
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
100
N.A.
86.6
N.A.
46.6
20
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
9
0
0
17
0
34
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
9
0
9
0
% D
% Glu:
0
9
9
0
0
0
9
9
9
0
0
50
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
9
17
42
9
0
0
9
0
0
0
50
9
0
% G
% His:
0
0
0
0
0
0
9
0
9
9
0
0
0
50
9
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
50
59
50
59
9
59
42
17
17
9
17
17
17
0
9
% K
% Leu:
0
17
17
0
17
0
0
0
0
0
0
9
9
9
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
9
0
9
9
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
9
9
0
0
0
9
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% R
% Ser:
17
0
9
17
9
9
9
34
42
42
9
0
9
0
17
% S
% Thr:
0
0
0
0
0
9
0
9
0
17
0
0
0
0
42
% T
% Val:
0
9
0
0
0
0
9
17
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
9
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _