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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP1
All Species:
22.42
Human Site:
S421
Identified Species:
44.85
UniProt:
Q13610
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13610
NP_008993.1
501
55828
S421
D
I
L
G
D
R
P
S
L
V
H
S
R
D
M
Chimpanzee
Pan troglodytes
XP_001162437
430
48207
W350
G
Q
I
E
R
V
T
W
N
H
F
S
P
C
H
Rhesus Macaque
Macaca mulatta
XP_001093636
372
41113
A293
M
S
L
G
K
P
A
A
S
L
A
V
H
T
D
Dog
Lupus familis
XP_531756
500
55840
S420
D
I
L
G
D
R
P
S
L
V
H
S
R
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q99LL5
501
55568
S420
D
I
L
G
D
R
P
S
L
I
H
S
R
D
M
Rat
Rattus norvegicus
XP_343187
500
55792
S420
D
I
L
G
E
R
P
S
L
I
H
S
R
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508747
534
59511
S450
D
I
L
G
D
K
P
S
L
V
H
S
R
D
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084632
504
56148
S425
D
I
M
L
D
K
P
S
L
V
H
S
R
N
M
Zebra Danio
Brachydanio rerio
NP_956586
490
54644
K409
C
S
A
D
K
H
V
K
I
W
D
I
L
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396674
460
52260
I381
I
I
K
V
W
D
I
I
E
D
T
K
P
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788925
939
103869
G821
D
T
Q
D
N
K
P
G
L
V
V
S
K
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21304
576
63785
V467
N
T
K
G
P
S
M
V
L
S
R
D
F
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
73.2
98.8
N.A.
89.8
90.2
N.A.
75.6
N.A.
69.8
70
N.A.
N.A.
38.9
N.A.
29.7
Protein Similarity:
100
85.8
73.6
99.1
N.A.
94
94.8
N.A.
84
N.A.
83.9
84.2
N.A.
N.A.
58.6
N.A.
40.1
P-Site Identity:
100
6.6
13.3
100
N.A.
93.3
86.6
N.A.
93.3
N.A.
73.3
0
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
13.3
26.6
100
N.A.
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
N.A.
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
9
0
0
9
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
59
0
0
17
42
9
0
0
0
9
9
9
0
59
9
% D
% Glu:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% F
% Gly:
9
0
0
59
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
9
50
0
9
0
9
% H
% Ile:
9
59
9
0
0
0
9
9
9
17
0
9
0
0
0
% I
% Lys:
0
0
17
0
17
25
0
9
0
0
0
9
9
0
0
% K
% Leu:
0
0
50
9
0
0
0
0
67
9
0
0
9
0
0
% L
% Met:
9
0
9
0
0
0
9
0
0
0
0
0
0
0
50
% M
% Asn:
9
0
0
0
9
0
0
0
9
0
0
0
0
9
9
% N
% Pro:
0
0
0
0
9
9
59
0
0
0
0
0
17
0
9
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
34
0
0
0
0
9
0
50
0
0
% R
% Ser:
0
17
0
0
0
9
0
50
9
9
0
67
0
9
0
% S
% Thr:
0
17
0
0
0
0
9
0
0
0
9
0
0
9
0
% T
% Val:
0
0
0
9
0
9
9
9
0
42
9
9
0
0
17
% V
% Trp:
0
0
0
0
9
0
0
9
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _