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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP1
All Species:
10.61
Human Site:
S487
Identified Species:
21.21
UniProt:
Q13610
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13610
NP_008993.1
501
55828
S487
S
A
R
N
S
S
I
S
G
P
F
G
S
R
S
Chimpanzee
Pan troglodytes
XP_001162437
430
48207
L416
Y
V
K
I
W
D
I
L
G
D
R
P
S
L
V
Rhesus Macaque
Macaca mulatta
XP_001093636
372
41113
G359
A
R
N
S
S
I
S
G
P
F
G
S
R
S
S
Dog
Lupus familis
XP_531756
500
55840
S486
N
T
R
S
S
S
I
S
G
P
F
G
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LL5
501
55568
S486
G
T
K
G
L
S
V
S
G
P
C
G
S
R
S
Rat
Rattus norvegicus
XP_343187
500
55792
S486
S
T
K
G
L
S
V
S
D
P
C
R
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508747
534
59511
G516
I
P
T
N
S
P
V
G
S
S
L
A
S
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084632
504
56148
E491
T
S
L
D
S
A
S
E
K
D
E
A
S
G
T
Zebra Danio
Brachydanio rerio
NP_956586
490
54644
V475
F
G
S
R
E
R
L
V
A
N
T
V
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396674
460
52260
D447
M
D
V
T
E
N
M
D
S
M
I
L
N
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788925
939
103869
Y887
P
H
P
S
E
I
A
Y
R
G
Q
S
S
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21304
576
63785
K533
R
A
K
E
E
A
Q
K
I
G
K
S
S
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
73.2
98.8
N.A.
89.8
90.2
N.A.
75.6
N.A.
69.8
70
N.A.
N.A.
38.9
N.A.
29.7
Protein Similarity:
100
85.8
73.6
99.1
N.A.
94
94.8
N.A.
84
N.A.
83.9
84.2
N.A.
N.A.
58.6
N.A.
40.1
P-Site Identity:
100
20
13.3
80
N.A.
53.3
40
N.A.
26.6
N.A.
13.3
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
93.3
N.A.
66.6
53.3
N.A.
33.3
N.A.
46.6
20
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
17
9
0
9
0
0
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% C
% Asp:
0
9
0
9
0
9
0
9
9
17
0
0
0
0
0
% D
% Glu:
0
0
0
9
34
0
0
9
0
0
9
0
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% F
% Gly:
9
9
0
17
0
0
0
17
34
17
9
25
0
25
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
17
25
0
9
0
9
0
0
0
9
% I
% Lys:
0
0
34
0
0
0
0
9
9
0
9
0
0
0
0
% K
% Leu:
0
0
9
0
17
0
9
9
0
0
9
9
0
9
0
% L
% Met:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
9
17
0
9
0
0
0
9
0
0
9
0
9
% N
% Pro:
9
9
9
0
0
9
0
0
9
34
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% Q
% Arg:
9
9
17
9
0
9
0
0
9
0
9
9
9
34
0
% R
% Ser:
17
9
9
25
42
34
17
34
17
9
0
25
84
17
50
% S
% Thr:
9
25
9
9
0
0
0
0
0
0
9
0
0
9
9
% T
% Val:
0
9
9
0
0
0
25
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _