KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP1
All Species:
24.55
Human Site:
Y129
Identified Species:
49.09
UniProt:
Q13610
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13610
NP_008993.1
501
55828
Y129
G
S
N
D
Q
D
P
Y
V
T
L
K
D
T
E
Chimpanzee
Pan troglodytes
XP_001162437
430
48207
Q64
S
P
S
E
D
G
M
Q
S
A
R
T
Q
A
R
Rhesus Macaque
Macaca mulatta
XP_001093636
372
41113
Dog
Lupus familis
XP_531756
500
55840
Y128
G
S
N
D
Q
D
P
Y
V
T
L
K
D
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99LL5
501
55568
Y128
G
S
N
D
Q
D
P
Y
V
T
L
K
D
T
E
Rat
Rattus norvegicus
XP_343187
500
55792
Y128
G
S
N
D
Q
D
P
Y
V
T
L
K
D
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508747
534
59511
Y158
G
S
N
E
H
D
P
Y
V
T
I
K
D
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084632
504
56148
Y129
S
S
N
D
E
D
A
Y
V
T
L
K
N
T
E
Zebra Danio
Brachydanio rerio
NP_956586
490
54644
N121
G
L
T
V
F
G
T
N
E
E
D
P
Y
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396674
460
52260
I95
N
I
N
N
I
A
I
I
E
K
N
G
K
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788925
939
103869
T532
N
N
D
D
P
Y
I
T
L
K
E
D
R
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21304
576
63785
S124
K
G
E
D
P
Y
I
S
L
P
N
Q
E
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
73.2
98.8
N.A.
89.8
90.2
N.A.
75.6
N.A.
69.8
70
N.A.
N.A.
38.9
N.A.
29.7
Protein Similarity:
100
85.8
73.6
99.1
N.A.
94
94.8
N.A.
84
N.A.
83.9
84.2
N.A.
N.A.
58.6
N.A.
40.1
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
80
N.A.
73.3
6.6
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
13.3
0
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
6.6
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
59
9
50
0
0
0
0
9
9
42
17
0
% D
% Glu:
0
0
9
17
9
0
0
0
17
9
9
0
9
9
59
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
9
0
0
0
17
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
25
9
0
0
9
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
17
0
50
9
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
17
0
42
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
59
9
0
0
0
9
0
0
17
0
9
0
0
% N
% Pro:
0
9
0
0
17
0
42
0
0
9
0
9
0
0
9
% P
% Gln:
0
0
0
0
34
0
0
9
0
0
0
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% R
% Ser:
17
50
9
0
0
0
0
9
9
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
9
9
0
50
0
9
0
50
9
% T
% Val:
0
0
0
9
0
0
0
0
50
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
50
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _