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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP1
All Species:
19.09
Human Site:
Y177
Identified Species:
38.18
UniProt:
Q13610
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13610
NP_008993.1
501
55828
Y177
N
Q
E
E
D
S
F
Y
V
H
H
D
I
L
L
Chimpanzee
Pan troglodytes
XP_001162437
430
48207
P106
K
Y
D
E
E
G
D
P
D
A
E
T
L
G
E
Rhesus Macaque
Macaca mulatta
XP_001093636
372
41113
G49
K
L
Q
E
G
G
G
G
S
D
E
E
E
I
G
Dog
Lupus familis
XP_531756
500
55840
Y176
N
Q
E
E
D
S
F
Y
V
H
H
D
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LL5
501
55568
Y176
N
Q
E
E
E
S
F
Y
V
H
H
D
I
L
L
Rat
Rattus norvegicus
XP_343187
500
55792
Y176
N
Q
E
E
E
S
F
Y
V
H
H
D
I
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508747
534
59511
Y206
N
Q
E
E
D
S
F
Y
V
H
H
D
I
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084632
504
56148
D181
D
S
F
Y
V
H
H
D
I
L
L
P
A
Y
P
Zebra Danio
Brachydanio rerio
NP_956586
490
54644
V165
C
C
N
L
E
I
H
V
Y
N
S
E
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396674
460
52260
L137
V
E
G
D
A
S
I
L
E
I
F
V
Y
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788925
939
103869
G577
Y
V
Y
N
E
E
E
G
V
L
Y
V
H
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21304
576
63785
S223
D
Y
K
V
G
S
N
S
E
E
A
A
N
Y
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
73.2
98.8
N.A.
89.8
90.2
N.A.
75.6
N.A.
69.8
70
N.A.
N.A.
38.9
N.A.
29.7
Protein Similarity:
100
85.8
73.6
99.1
N.A.
94
94.8
N.A.
84
N.A.
83.9
84.2
N.A.
N.A.
58.6
N.A.
40.1
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
93.3
N.A.
100
N.A.
0
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
100
N.A.
13.3
20
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
9
9
9
9
0
9
% A
% Cys:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
9
25
0
9
9
9
9
0
42
0
9
9
% D
% Glu:
0
9
42
59
42
9
9
0
17
9
17
17
17
0
9
% E
% Phe:
0
0
9
0
0
0
42
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
17
17
9
17
0
0
0
0
0
9
17
% G
% His:
0
0
0
0
0
9
17
0
0
42
42
0
9
9
0
% H
% Ile:
0
0
0
0
0
9
9
0
9
9
0
0
42
9
0
% I
% Lys:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
9
0
0
0
9
0
17
9
0
9
42
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
9
9
0
0
9
0
0
9
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% P
% Gln:
0
42
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
59
0
9
9
0
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
9
9
0
9
9
0
0
9
50
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
9
9
0
0
0
42
9
0
9
0
9
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _