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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTMR2
All Species:
27.27
Human Site:
Y580
Identified Species:
54.55
UniProt:
Q13614
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13614
NP_057240.3
643
73381
Y580
L
E
L
W
V
G
Y
Y
I
R
W
N
P
R
M
Chimpanzee
Pan troglodytes
XP_001146719
676
76956
Y613
L
E
L
W
V
G
Y
Y
I
R
W
N
P
R
M
Rhesus Macaque
Macaca mulatta
XP_001092784
643
73239
Y580
L
E
L
W
V
G
Y
Y
I
R
W
N
P
R
M
Dog
Lupus familis
XP_848239
643
73390
Y580
L
E
L
W
V
G
Y
Y
V
R
W
N
P
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D1
643
73227
Y580
L
E
L
W
V
G
Y
Y
I
R
W
N
P
R
M
Rat
Rattus norvegicus
Q6AXQ4
602
69333
Q548
W
N
P
R
I
R
Q
Q
P
H
P
M
E
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511132
656
74861
Y594
L
E
L
W
V
G
Y
Y
I
R
W
N
P
R
M
Chicken
Gallus gallus
Q5ZIV1
571
65950
Q518
W
N
P
R
M
K
P
Q
E
P
V
H
N
R
Y
Frog
Xenopus laevis
Q52KU6
602
69712
Q547
W
N
P
R
I
R
Q
Q
Q
P
N
P
V
E
Q
Zebra Danio
Brachydanio rerio
A0JMK5
620
71091
Y556
L
Q
L
W
V
S
Y
Y
I
R
W
N
P
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22712
1006
113596
H627
V
I
N
L
R
V
W
H
E
V
F
A
D
E
E
Sea Urchin
Strong. purpuratus
XP_788958
678
77013
Y613
R
I
E
L
W
T
S
Y
Y
I
R
W
N
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
99.2
98.4
N.A.
97.1
60.5
N.A.
90
85.3
62
71.8
N.A.
N.A.
N.A.
22.2
60.4
Protein Similarity:
100
95.1
99.6
99.6
N.A.
98.5
74.4
N.A.
95.2
87.4
75.7
84.2
N.A.
N.A.
N.A.
37.8
75.6
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
100
6.6
0
86.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
20
6.6
93.3
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
50
9
0
0
0
0
0
17
0
0
0
9
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
9
0
0
0
% H
% Ile:
0
17
0
0
17
0
0
0
50
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
59
0
59
17
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
59
% M
% Asn:
0
25
9
0
0
0
0
0
0
0
9
59
17
0
0
% N
% Pro:
0
0
25
0
0
0
9
0
9
17
9
9
59
9
0
% P
% Gln:
0
9
0
0
0
0
17
25
9
0
0
0
0
9
9
% Q
% Arg:
9
0
0
25
9
17
0
0
0
59
9
0
0
67
17
% R
% Ser:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
59
9
0
0
9
9
9
0
9
0
0
% V
% Trp:
25
0
0
59
9
0
9
0
0
0
59
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
59
67
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _