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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
28.18
Human Site:
S234
Identified Species:
44.29
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
S234
V
Y
K
E
S
F
E
S
Q
F
L
A
D
T
E
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
R230
D
T
E
R
F
Y
T
R
E
S
T
E
F
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
S234
V
Y
K
E
S
F
E
S
Q
F
L
A
D
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
S234
V
Y
K
E
S
F
E
S
Q
F
L
A
D
T
E
Rat
Rattus norvegicus
Q9JJ31
780
90872
A236
N
Y
M
K
Y
A
D
A
K
L
K
E
E
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
S234
V
Y
K
E
S
F
E
S
Q
F
L
A
D
T
E
Chicken
Gallus gallus
XP_418878
774
89674
S232
V
Y
K
E
S
F
E
S
Q
F
L
A
D
T
E
Frog
Xenopus laevis
Q6DE95
768
88933
M219
M
S
A
E
F
F
Q
M
E
S
Q
K
F
L
A
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
T235
V
Y
K
E
Y
F
E
T
Q
F
L
A
D
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N225
V
Y
K
Q
N
F
E
N
K
F
I
A
D
T
S
Honey Bee
Apis mellifera
XP_394044
777
89569
N238
V
Y
S
N
S
F
E
N
V
F
L
E
D
T
E
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
V234
V
Y
K
E
F
F
E
V
K
F
L
E
A
T
R
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
S233
V
Y
K
D
S
F
E
S
Q
F
L
S
E
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S224
C
P
D
Y
M
L
K
S
E
E
C
L
K
K
E
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
P227
Y
I
Q
V
F
E
K
P
F
L
K
K
T
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
0
N.A.
100
N.A.
100
6.6
N.A.
100
100
13.3
86.6
N.A.
60
66.6
60
80
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
46.6
N.A.
100
100
33.3
93.3
N.A.
93.3
73.3
66.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
7
0
0
0
47
7
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
7
7
0
0
7
0
0
0
0
0
54
0
0
% D
% Glu:
0
0
7
54
0
7
67
0
20
7
0
27
14
7
67
% E
% Phe:
0
0
0
0
27
74
0
0
7
67
0
0
14
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
60
7
0
0
14
0
20
0
14
14
7
7
7
% K
% Leu:
0
0
0
0
0
7
0
0
0
14
60
7
0
14
0
% L
% Met:
7
0
7
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
7
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
7
0
47
0
7
0
0
7
7
% Q
% Arg:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% R
% Ser:
0
7
7
0
47
0
0
47
0
14
0
7
0
0
7
% S
% Thr:
0
7
0
0
0
0
7
7
0
0
7
0
7
67
0
% T
% Val:
67
0
0
7
0
0
0
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
74
0
7
14
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _