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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
35.15
Human Site:
S528
Identified Species:
55.24
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
S528
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
S512
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
S528
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
S528
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Rat
Rattus norvegicus
Q9JJ31
780
90872
A520
M
H
K
N
N
K
L
A
L
P
A
D
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
S528
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Chicken
Gallus gallus
XP_418878
774
89674
S526
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Frog
Xenopus laevis
Q6DE95
768
88933
T494
F
R
Q
H
L
Q
T
T
G
V
S
L
G
G
V
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
S529
F
K
K
H
L
T
N
S
E
P
L
D
L
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
K527
F
K
Q
Y
L
A
E
K
N
L
T
M
E
I
D
Honey Bee
Apis mellifera
XP_394044
777
89569
S532
F
R
R
H
L
T
N
S
A
E
P
L
D
I
D
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
M532
F
K
E
K
K
A
D
M
L
G
Q
K
S
V
E
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
S527
F
K
N
H
L
A
S
S
E
S
L
D
I
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N495
F
E
D
Y
L
G
S
N
P
A
A
N
P
G
I
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
E543
F
A
V
A
L
K
N
E
P
D
Y
S
K
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
20
100
N.A.
20
40
13.3
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
100
100
40
100
N.A.
33.3
53.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
20
0
7
7
7
14
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
0
7
0
60
7
54
14
% D
% Glu:
0
7
7
0
0
0
7
7
54
7
0
0
7
0
7
% E
% Phe:
94
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% F
% Gly:
0
0
0
0
0
7
0
0
7
7
0
0
7
14
0
% G
% His:
0
7
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
7
% I
% Lys:
0
67
54
7
7
14
0
7
0
0
0
7
7
0
7
% K
% Leu:
0
0
0
0
87
0
7
0
14
7
54
14
47
0
0
% L
% Met:
7
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
7
7
0
60
7
7
0
0
7
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
14
54
7
0
7
0
0
% P
% Gln:
0
0
14
0
0
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
14
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
14
60
0
7
7
7
14
0
0
% S
% Thr:
0
0
0
0
0
54
7
7
0
0
7
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
7
0
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _