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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
24.85
Human Site:
S72
Identified Species:
39.05
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
S72
A
G
V
P
P
S
K
S
K
K
G
Q
T
P
G
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
L72
A
G
F
V
G
L
E
L
Y
K
R
L
K
E
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
S72
A
G
V
P
P
S
K
S
K
K
G
Q
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
S72
A
G
V
P
P
S
K
S
K
K
G
Q
T
P
G
Rat
Rattus norvegicus
Q9JJ31
780
90872
L70
Q
A
L
K
E
D
I
L
E
F
I
K
Q
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
S72
A
G
V
P
P
S
K
S
K
K
G
Q
T
P
G
Chicken
Gallus gallus
XP_418878
774
89674
S72
A
G
V
P
P
S
K
S
K
K
G
Q
T
P
G
Frog
Xenopus laevis
Q6DE95
768
88933
A61
F
E
E
L
Y
R
N
A
Y
T
M
V
L
H
K
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
S73
G
P
A
P
S
K
P
S
K
K
T
P
T
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
R63
V
S
A
A
P
S
G
R
S
S
G
K
T
G
G
Honey Bee
Apis mellifera
XP_394044
777
89569
K76
T
R
T
S
T
K
S
K
K
G
Q
I
S
Q
G
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
S68
G
E
D
G
R
A
E
S
S
T
P
A
R
T
A
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
S71
A
R
T
T
S
A
K
S
K
K
G
T
V
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y63
H
D
Y
S
Q
Q
L
Y
D
K
Y
R
E
A
F
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S66
C
V
N
K
S
R
S
S
G
H
F
S
T
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
20
N.A.
100
N.A.
100
0
N.A.
100
100
0
46.6
N.A.
33.3
13.3
6.6
46.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
20
N.A.
100
100
6.6
46.6
N.A.
40
20
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
7
14
7
0
14
0
7
0
0
0
7
0
14
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
7
0
0
7
0
0
0
0
7
0
% D
% Glu:
0
14
7
0
7
0
14
0
7
0
0
0
7
7
0
% E
% Phe:
7
0
7
0
0
0
0
0
0
7
7
0
0
0
14
% F
% Gly:
14
40
0
7
7
0
7
0
7
7
47
0
0
7
60
% G
% His:
7
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
7
7
0
0
0
% I
% Lys:
0
0
0
14
0
14
40
7
54
60
0
14
7
0
7
% K
% Leu:
0
0
7
7
0
7
7
14
0
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
40
40
0
7
0
0
0
7
7
0
40
0
% P
% Gln:
7
0
0
0
7
7
0
0
0
0
7
34
7
14
7
% Q
% Arg:
0
14
0
0
7
14
0
7
0
0
7
7
7
0
0
% R
% Ser:
0
7
0
14
20
40
14
60
14
7
0
7
7
0
7
% S
% Thr:
7
0
14
7
7
0
0
0
0
14
7
7
54
7
0
% T
% Val:
7
7
34
7
0
0
0
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
7
14
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _