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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
33.33
Human Site:
T198
Identified Species:
52.38
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
T198
R
N
G
E
T
I
N
T
R
L
I
S
G
V
V
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
L195
V
V
Q
S
Y
V
E
L
G
L
N
E
D
D
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
T198
R
N
G
E
T
I
N
T
R
L
I
S
G
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
T198
R
N
G
E
T
I
N
T
R
L
I
S
G
V
V
Rat
Rattus norvegicus
Q9JJ31
780
90872
Q196
S
N
P
E
D
K
L
Q
I
Y
R
D
N
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
T198
R
N
G
E
T
I
N
T
R
L
I
S
G
V
V
Chicken
Gallus gallus
XP_418878
774
89674
T196
I
E
V
K
G
T
N
T
K
I
L
S
I
F
I
Frog
Xenopus laevis
Q6DE95
768
88933
R184
V
V
D
R
G
A
I
R
N
A
C
Q
M
L
M
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
T199
R
N
G
E
T
I
N
T
R
L
I
S
G
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
R189
R
Q
G
K
L
I
N
R
S
L
V
R
D
V
I
Honey Bee
Apis mellifera
XP_394044
777
89569
T202
R
N
G
E
T
I
N
T
R
L
V
S
G
V
I
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
S194
R
T
G
S
M
I
N
S
R
Y
I
S
G
V
V
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
T197
R
H
G
E
P
I
N
T
R
L
V
S
G
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y188
G
M
G
Q
M
E
R
Y
E
E
D
F
E
S
F
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
R192
R
E
G
Q
I
I
Q
R
S
N
I
S
T
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
13.3
N.A.
100
20
0
100
N.A.
40
86.6
66.6
73.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
13.3
N.A.
100
53.3
13.3
100
N.A.
60
100
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
0
0
0
7
7
14
7
0
% D
% Glu:
0
14
0
54
0
7
7
0
7
7
0
7
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
14
7
% F
% Gly:
7
0
74
0
14
0
0
0
7
0
0
0
54
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
67
7
0
7
7
47
0
7
0
34
% I
% Lys:
0
0
0
14
0
7
0
0
7
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
7
7
0
60
7
0
0
7
0
% L
% Met:
0
7
0
0
14
0
0
0
0
0
0
0
7
0
7
% M
% Asn:
0
47
0
0
0
0
67
0
7
7
7
0
7
0
0
% N
% Pro:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
14
0
0
7
7
0
0
0
7
0
0
0
% Q
% Arg:
67
0
0
7
0
0
7
20
54
0
7
7
0
0
0
% R
% Ser:
7
0
0
14
0
0
0
7
14
0
0
67
0
7
0
% S
% Thr:
0
7
0
0
40
7
0
54
0
0
0
0
7
0
0
% T
% Val:
14
14
7
0
0
7
0
0
0
0
20
0
0
60
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _