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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
28.79
Human Site:
Y563
Identified Species:
45.24
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
Y563
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
Y547
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
Y563
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
Y563
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Rat
Rattus norvegicus
Q9JJ31
780
90872
I555
P
T
E
L
E
D
L
I
P
E
V
E
E
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
Y563
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Chicken
Gallus gallus
XP_418878
774
89674
Y561
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Frog
Xenopus laevis
Q6DE95
768
88933
R529
C
N
I
P
P
A
P
R
H
A
F
E
I
F
R
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
Y564
P
S
E
L
E
R
S
Y
Q
R
F
T
A
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S562
L
P
S
E
L
E
R
S
V
R
Q
F
N
E
F
Honey Bee
Apis mellifera
XP_394044
777
89569
S567
L
P
T
E
L
E
R
S
V
H
R
F
T
T
F
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
T567
L
P
Q
Q
L
S
K
T
I
E
I
F
G
Q
F
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
F562
P
S
E
L
E
R
S
F
Q
R
F
T
T
F
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
K530
N
L
P
S
E
M
I
K
C
V
E
V
F
K
G
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
E578
V
E
F
K
L
P
K
E
L
V
P
S
H
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
40
N.A.
100
100
13.3
100
N.A.
6.6
0
0
86.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
46.6
N.A.
100
100
20
100
N.A.
13.3
6.6
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
7
0
0
47
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
60
14
67
14
0
7
0
14
7
14
7
14
0
% E
% Phe:
0
0
7
0
0
0
0
7
0
0
60
20
7
67
20
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
0
7
7
7
0
7
0
7
0
0
% I
% Lys:
0
0
0
7
0
0
14
7
0
0
0
0
0
7
7
% K
% Leu:
20
7
0
60
27
0
7
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
60
20
7
7
7
7
7
0
7
0
7
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
54
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
0
54
14
7
0
60
7
0
0
0
7
% R
% Ser:
0
54
7
7
0
7
54
14
0
0
0
7
0
0
0
% S
% Thr:
0
7
7
0
0
0
0
7
0
0
0
54
14
7
0
% T
% Val:
7
0
0
0
0
0
0
0
14
14
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _