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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
28.79
Human Site:
Y672
Identified Species:
45.24
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
Y672
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
Y656
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
Y672
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
Y672
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Rat
Rattus norvegicus
Q9JJ31
780
90872
K676
N
Q
D
F
S
L
I
K
N
A
K
V
Q
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
Y672
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Chicken
Gallus gallus
XP_418878
774
89674
Y670
P
D
T
L
I
K
L
Y
L
G
Y
K
N
K
K
Frog
Xenopus laevis
Q6DE95
768
88933
Q664
H
M
F
T
V
N
D
Q
F
T
S
K
L
H
R
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
F673
P
D
T
L
I
K
L
F
L
G
Y
K
N
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
F670
P
E
S
T
V
E
L
F
L
D
Y
K
N
K
K
Honey Bee
Apis mellifera
XP_394044
777
89569
F673
P
L
S
T
V
E
L
F
T
G
Y
K
N
K
K
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
N675
M
T
A
T
V
S
L
N
K
A
Y
M
N
K
K
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
Y666
P
T
T
E
V
K
L
Y
Q
G
Y
K
N
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N638
Q
N
D
A
F
E
F
N
S
K
F
T
D
R
M
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S692
P
E
T
Q
F
K
L
S
R
P
Y
K
A
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
6.6
93.3
N.A.
53.3
53.3
33.3
73.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
20
100
N.A.
86.6
80
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
0
0
14
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
14
0
0
0
7
0
0
7
0
0
7
0
0
% D
% Glu:
0
14
0
7
0
20
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
7
14
0
7
20
7
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
47
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
60
0
7
7
7
7
80
0
80
80
% K
% Leu:
0
7
0
47
0
7
80
0
54
0
0
0
7
7
0
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% M
% Asn:
7
7
0
0
0
7
0
14
7
0
0
0
74
0
0
% N
% Pro:
74
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
7
7
0
7
0
0
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
14
% R
% Ser:
0
0
14
0
7
7
0
7
7
0
7
0
0
0
0
% S
% Thr:
0
14
60
27
0
0
0
0
7
7
0
7
0
0
0
% T
% Val:
0
0
0
0
34
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
80
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _