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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
48.86
Human Site:
Y772
Identified Species:
76.79
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
Y772
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
Y756
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
Y772
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
Y772
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Rat
Rattus norvegicus
Q9JJ31
780
90872
F776
D
E
A
D
I
N
T
F
I
Y
M
A
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
Y772
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Chicken
Gallus gallus
XP_418878
774
89674
Y770
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Frog
Xenopus laevis
Q6DE95
768
88933
Y764
T
P
E
D
R
K
V
Y
T
Y
V
A
_
_
_
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
Y773
V
D
G
E
K
D
T
Y
S
Y
L
A
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
Y770
M
E
G
H
K
D
T
Y
S
Y
L
A
_
_
_
Honey Bee
Apis mellifera
XP_394044
777
89569
Y773
T
E
G
Q
K
D
T
Y
S
Y
L
A
_
_
_
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
Y776
T
E
G
Q
K
D
L
Y
E
Y
L
A
_
_
_
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
Y766
V
D
G
E
K
D
V
Y
S
Y
L
A
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
F734
D
K
E
N
P
N
M
F
R
Y
L
A
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Y811
R
G
D
D
G
E
S
Y
A
Y
L
A
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
25
N.A.
100
100
25
100
N.A.
75
75
58.3
91.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
66.6
N.A.
100
100
58.3
100
N.A.
91.6
91.6
75
91.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
25
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
41.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
0
100
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
54
7
20
0
74
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
27
14
54
0
7
0
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
7
74
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
74
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
87
0
0
0
0
% L
% Met:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
14
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
67
0
0
0
0
0
0
% S
% Thr:
20
0
0
0
0
0
67
0
7
0
0
0
0
0
0
% T
% Val:
54
0
0
0
0
0
14
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
100
100
100
% _