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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL1
All Species:
36.67
Human Site:
Y99
Identified Species:
57.62
UniProt:
Q13616
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13616
NP_003583.2
776
89679
Y99
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Chimpanzee
Pan troglodytes
XP_001165296
760
88111
V99
E
D
L
M
D
E
S
V
L
K
F
Y
T
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848402
776
89643
Y99
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX6
776
89673
Y99
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Rat
Rattus norvegicus
Q9JJ31
780
90872
W97
L
K
A
Y
I
V
E
W
R
K
F
F
T
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505554
776
89705
Y99
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Chicken
Gallus gallus
XP_418878
774
89674
Y99
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Frog
Xenopus laevis
Q6DE95
768
88933
K88
V
T
E
H
L
I
N
K
V
R
E
D
V
L
N
Zebra Danio
Brachydanio rerio
NP_955953
777
90010
Y100
L
K
E
F
L
K
N
Y
L
T
N
L
L
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
L90
E
Q
F
L
K
S
Y
L
S
E
L
L
T
K
F
Honey Bee
Apis mellifera
XP_394044
777
89569
Y103
L
R
D
F
L
R
N
Y
L
I
S
L
L
K
H
Nematode Worm
Caenorhab. elegans
Q17389
780
89509
Y95
V
E
E
Y
V
K
A
Y
V
I
A
V
C
E
K
Sea Urchin
Strong. purpuratus
XP_794360
770
89058
Y98
L
R
D
F
L
R
D
Y
L
V
S
L
R
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
M90
R
E
K
H
D
E
F
M
L
R
E
L
F
K
R
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Y93
I
Y
E
K
L
K
N
Y
L
K
N
Y
I
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
99.7
N.A.
99.8
31.5
N.A.
99.7
97
31.8
96.5
N.A.
63.6
78.2
46.9
81.7
Protein Similarity:
100
97.9
N.A.
99.7
N.A.
99.8
53.4
N.A.
99.8
98
54.5
97.6
N.A.
77.9
87.9
65.5
91.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
13.3
N.A.
100
100
20
100
N.A.
13.3
60
20
46.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
40
N.A.
100
100
46.6
100
N.A.
20
86.6
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
7
14
0
14
0
7
0
0
0
0
7
0
0
47
% D
% Glu:
14
14
60
0
0
14
7
0
0
7
14
0
0
7
0
% E
% Phe:
0
0
7
54
0
0
7
0
0
0
14
7
7
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
7
7
0
0
0
14
0
0
7
0
0
% I
% Lys:
0
47
7
7
7
54
0
7
0
20
0
0
0
60
7
% K
% Leu:
60
0
7
7
67
0
0
7
74
0
7
67
47
14
0
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
60
0
0
0
47
0
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
20
7
% Q
% Arg:
7
14
0
0
0
14
0
0
7
14
0
0
7
0
7
% R
% Ser:
0
0
0
0
0
7
7
0
7
0
14
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
40
0
0
20
0
0
% T
% Val:
14
0
0
0
7
7
0
7
14
7
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
14
0
0
7
67
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _