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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL2
All Species:
36.67
Human Site:
Y203
Identified Species:
67.22
UniProt:
Q13617
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13617
NP_003582.2
745
86983
Y203
K
K
F
P
L
K
F
Y
Q
E
I
F
E
S
P
Chimpanzee
Pan troglodytes
XP_507738
829
95741
Y305
K
K
F
P
L
K
F
Y
Q
E
I
F
E
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535140
745
86988
Y203
K
K
F
P
L
K
F
Y
Q
E
I
F
E
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H8
745
86858
Y203
K
K
F
P
L
K
F
Y
Q
G
I
F
V
S
P
Rat
Rattus norvegicus
Q9JJ31
780
90872
Y198
P
E
D
K
L
Q
I
Y
R
D
N
F
E
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508563
745
87017
Y203
K
K
F
P
L
K
F
Y
Q
E
I
F
E
C
P
Chicken
Gallus gallus
NP_001026141
688
80276
I158
M
I
E
P
L
Q
A
I
L
I
R
M
L
L
R
Frog
Xenopus laevis
Q6GPF3
768
88937
Y201
G
L
E
G
R
S
V
Y
E
E
D
F
E
A
P
Zebra Danio
Brachydanio rerio
XP_002666627
745
86977
Y203
K
K
F
P
L
K
F
Y
Q
E
I
F
E
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
Y219
E
Q
Q
K
L
S
V
Y
K
Q
N
F
E
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17390
776
89707
Y219
R
E
S
T
T
A
F
Y
Q
E
S
F
E
K
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y188
G
M
G
Q
M
E
R
Y
E
E
D
F
E
S
F
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Y220
K
K
L
N
L
N
V
Y
I
Q
V
F
E
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
N.A.
99.4
N.A.
97.3
28.9
N.A.
96.5
83.3
28.1
92.2
N.A.
33
N.A.
43
N.A.
Protein Similarity:
100
87.6
N.A.
99.5
N.A.
99.3
50.7
N.A.
98.6
86.4
51.5
96.9
N.A.
55.1
N.A.
64.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
26.6
N.A.
93.3
13.3
33.3
93.3
N.A.
26.6
N.A.
46.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
53.3
N.A.
93.3
20
46.6
93.3
N.A.
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
8
16
0
0
0
0
% D
% Glu:
8
16
16
0
0
8
0
0
16
62
0
0
85
0
0
% E
% Phe:
0
0
47
0
0
0
54
0
0
0
0
93
0
0
8
% F
% Gly:
16
0
8
8
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
8
8
8
47
0
0
0
0
% I
% Lys:
54
54
0
16
0
47
0
0
8
0
0
0
0
24
8
% K
% Leu:
0
8
8
0
77
0
0
0
8
0
0
0
8
8
0
% L
% Met:
8
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
16
0
0
8
0
% N
% Pro:
8
0
0
54
0
0
0
0
0
0
0
0
0
0
70
% P
% Gln:
0
8
8
8
0
16
0
0
54
16
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
0
8
0
8
0
0
0
8
% R
% Ser:
0
0
8
0
0
16
0
0
0
0
8
0
0
39
0
% S
% Thr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
24
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _