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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL2
All Species:
30.3
Human Site:
Y394
Identified Species:
55.56
UniProt:
Q13617
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13617
NP_003582.2
745
86983
Y394
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Chimpanzee
Pan troglodytes
XP_507738
829
95741
Y478
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535140
745
86988
Y394
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H8
745
86858
Y394
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Rat
Rattus norvegicus
Q9JJ31
780
90872
D413
E
L
L
A
N
Y
C
D
M
L
L
R
K
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508563
745
87017
Y394
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Chicken
Gallus gallus
NP_001026141
688
80276
K319
H
N
I
I
R
Q
E
K
R
N
D
M
A
N
M
Frog
Xenopus laevis
Q6GPF3
768
88937
F391
S
P
E
Y
L
S
L
F
I
D
D
K
L
K
K
Zebra Danio
Brachydanio rerio
XP_002666627
745
86977
Y394
A
P
E
L
L
A
K
Y
C
D
N
L
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
Y424
S
P
E
L
L
A
K
Y
C
D
L
L
L
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17390
776
89707
Y411
A
S
E
R
L
A
R
Y
T
D
G
L
L
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
C392
A
E
L
L
A
T
F
C
D
N
I
L
K
K
G
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
A440
S
K
T
S
E
M
L
A
K
Y
S
D
I
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
N.A.
99.4
N.A.
97.3
28.9
N.A.
96.5
83.3
28.1
92.2
N.A.
33
N.A.
43
N.A.
Protein Similarity:
100
87.6
N.A.
99.5
N.A.
99.3
50.7
N.A.
98.6
86.4
51.5
96.9
N.A.
55.1
N.A.
64.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
0
46.6
100
N.A.
86.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
33.3
73.3
100
N.A.
93.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
0
8
8
62
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
54
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
70
16
8
0
0
0
% D
% Glu:
8
8
70
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
8
0
8
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
54
8
8
0
0
8
16
77
70
% K
% Leu:
0
8
16
62
70
0
16
0
0
8
16
70
70
8
8
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
8
% M
% Asn:
0
8
0
0
8
0
0
0
0
16
47
0
0
8
0
% N
% Pro:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
24
8
0
8
0
8
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _