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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL2
All Species:
26.67
Human Site:
Y568
Identified Species:
48.89
UniProt:
Q13617
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13617
NP_003582.2
745
86983
Y568
T
G
E
V
K
M
N
Y
L
G
K
P
Y
V
A
Chimpanzee
Pan troglodytes
XP_507738
829
95741
Y652
T
G
E
V
K
M
N
Y
L
G
K
P
Y
V
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535140
745
86988
Y568
T
G
E
V
K
M
N
Y
L
G
K
P
Y
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H8
745
86858
Y568
T
G
E
V
K
M
N
Y
L
G
K
P
Y
V
A
Rat
Rattus norvegicus
Q9JJ31
780
90872
N586
N
G
I
I
T
F
K
N
E
V
G
Q
Y
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508563
745
87017
Y568
T
G
E
V
K
M
N
Y
L
C
K
P
Y
V
A
Chicken
Gallus gallus
NP_001026141
688
80276
K501
C
G
Y
E
F
T
S
K
L
H
R
M
Y
T
D
Frog
Xenopus laevis
Q6GPF3
768
88937
S585
G
G
A
Q
V
T
G
S
N
T
R
K
H
I
L
Zebra Danio
Brachydanio rerio
XP_002666627
745
86977
Y568
T
G
E
V
K
M
N
Y
L
S
K
P
Y
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N597
L
I
M
N
V
N
R
N
N
S
S
T
Y
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17390
776
89707
Y599
Q
G
D
V
R
L
T
Y
L
D
K
Q
Y
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Q565
H
I
N
G
K
F
D
Q
K
A
I
E
L
I
V
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
P617
L
K
A
D
I
G
K
P
G
R
M
P
F
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
N.A.
99.4
N.A.
97.3
28.9
N.A.
96.5
83.3
28.1
92.2
N.A.
33
N.A.
43
N.A.
Protein Similarity:
100
87.6
N.A.
99.5
N.A.
99.3
50.7
N.A.
98.6
86.4
51.5
96.9
N.A.
55.1
N.A.
64.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
93.3
20
6.6
93.3
N.A.
6.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
93.3
33.3
26.6
93.3
N.A.
6.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
54
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
8
0
0
8
0
0
0
8
8
% D
% Glu:
0
0
47
8
0
0
0
0
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
16
0
0
0
0
0
0
8
0
8
% F
% Gly:
8
77
0
8
0
8
8
0
8
31
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
16
8
8
8
0
0
0
0
0
8
0
0
16
0
% I
% Lys:
0
8
0
0
54
0
16
8
8
0
54
8
0
0
0
% K
% Leu:
16
0
0
0
0
8
0
0
62
0
0
0
8
0
24
% L
% Met:
0
0
8
0
0
47
0
0
0
0
8
8
0
0
0
% M
% Asn:
8
0
8
8
0
8
47
16
16
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
54
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
8
0
0
0
16
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
0
8
16
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
8
0
16
8
0
0
0
0
% S
% Thr:
47
0
0
0
8
16
8
0
0
8
0
8
0
16
0
% T
% Val:
0
0
0
54
16
0
0
0
0
8
0
0
0
54
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
54
0
0
0
0
77
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _