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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL2
All Species:
27.65
Human Site:
Y741
Identified Species:
50.69
UniProt:
Q13617
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13617
NP_003582.2
745
86983
Y741
S
Q
A
S
A
D
E
Y
S
Y
V
A
_
_
_
Chimpanzee
Pan troglodytes
XP_507738
829
95741
Y825
S
Q
A
S
A
D
E
Y
S
Y
V
A
_
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535140
745
86988
Y741
S
Q
A
S
A
D
E
Y
S
Y
V
A
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H8
745
86858
Y741
S
Q
A
S
A
D
E
Y
S
Y
V
A
_
_
_
Rat
Rattus norvegicus
Q9JJ31
780
90872
F776
D
E
A
D
I
N
T
F
I
Y
M
A
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508563
745
87017
Y741
S
Q
A
S
A
D
E
Y
S
Y
V
A
_
_
_
Chicken
Gallus gallus
NP_001026141
688
80276
M666
V
C
S
N
D
I
K
M
F
S
V
L
S
V
V
Frog
Xenopus laevis
Q6GPF3
768
88937
Y764
T
P
E
D
R
K
V
Y
T
Y
V
A
_
_
_
Zebra Danio
Brachydanio rerio
XP_002666627
745
86977
Y741
S
Q
S
S
A
D
E
Y
S
Y
V
A
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
Y770
M
E
G
H
K
D
T
Y
S
Y
L
A
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17390
776
89707
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
F734
D
K
E
N
P
N
M
F
R
Y
L
A
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
N.A.
99.4
N.A.
97.3
28.9
N.A.
96.5
83.3
28.1
92.2
N.A.
33
N.A.
43
N.A.
Protein Similarity:
100
87.6
N.A.
99.5
N.A.
99.3
50.7
N.A.
98.6
86.4
51.5
96.9
N.A.
55.1
N.A.
64.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
25
N.A.
100
6.6
33.3
91.6
N.A.
41.6
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
58.3
N.A.
100
26.6
50
100
N.A.
58.3
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
16.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
58.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
0
47
0
0
0
0
0
0
77
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
16
8
54
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
16
0
0
0
47
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% L
% Met:
8
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
16
0
16
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
47
0
16
47
0
0
0
0
54
8
0
0
8
0
0
% S
% Thr:
8
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
0
0
62
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
77
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
77
77
77
% _