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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
38.79
Human Site:
S199
Identified Species:
56.89
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
S199
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
S188
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
S177
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Dog
Lupus familis
XP_534586
746
86477
S177
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
S199
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Rat
Rattus norvegicus
Q9JJ31
780
90872
Q196
S
N
P
E
D
K
L
Q
I
Y
R
D
N
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
A100
M
E
S
Q
K
F
L
A
E
N
S
A
S
V
Y
Chicken
Gallus gallus
XP_422620
768
88957
S199
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Frog
Xenopus laevis
Q6DE95
768
88933
S199
I
L
G
L
E
G
R
S
V
Y
E
E
D
F
E
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
S197
V
L
G
L
K
G
R
S
V
Y
E
E
D
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S217
D
A
E
Q
Q
K
L
S
V
Y
K
Q
N
F
E
Honey Bee
Apis mellifera
XP_625079
767
89385
Q196
L
L
G
I
N
S
R
Q
V
Y
E
E
D
F
E
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
T197
S
L
G
I
D
S
R
T
V
Y
E
D
E
F
E
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
S133
A
D
F
Y
R
M
E
S
Q
N
F
L
T
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
E186
E
I
G
M
G
Q
M
E
R
Y
E
E
D
F
E
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
E185
K
V
L
I
G
M
M
E
T
L
H
D
N
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
0
100
100
86.6
N.A.
33.3
66.6
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
20
100
100
100
N.A.
60
80
86.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
13
0
0
0
0
0
0
19
63
0
7
% D
% Glu:
7
7
7
7
44
0
7
13
7
0
69
63
7
7
82
% E
% Phe:
0
0
7
0
0
7
0
0
0
0
7
0
0
82
0
% F
% Gly:
0
0
69
0
13
50
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
44
7
0
19
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
13
13
0
0
0
0
7
0
0
0
0
% K
% Leu:
7
63
7
50
0
0
19
0
0
7
0
7
0
0
0
% L
% Met:
7
0
0
7
0
13
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
0
13
0
0
19
0
7
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
7
7
0
13
7
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
7
0
63
0
7
0
7
0
0
7
0
% R
% Ser:
13
0
7
0
0
13
0
63
0
0
7
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% T
% Val:
7
7
0
0
0
0
0
0
69
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
82
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _