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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
40.91
Human Site:
T515
Identified Species:
60
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T515
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
T504
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
T493
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Dog
Lupus familis
XP_534586
746
86477
T493
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T515
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Rat
Rattus norvegicus
Q9JJ31
780
90872
R538
L
N
A
G
A
W
S
R
S
S
E
K
V
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
R403
C
N
I
P
P
A
P
R
H
A
F
E
I
F
R
Chicken
Gallus gallus
XP_422620
768
88957
T515
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Frog
Xenopus laevis
Q6DE95
768
88933
T515
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
T513
L
T
T
G
Y
W
P
T
Q
S
A
T
P
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
M531
L
A
E
K
N
L
T
M
E
I
D
F
G
I
E
Honey Bee
Apis mellifera
XP_625079
767
89385
T513
L
T
T
G
F
W
P
T
Q
S
A
T
P
K
C
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
V521
T
A
G
V
W
P
T
V
Q
C
N
P
V
V
L
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
T436
L
T
T
G
F
W
P
T
Q
S
A
T
P
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
A497
D
Y
L
G
S
N
P
A
A
N
P
G
I
D
L
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
H489
E
M
Y
Q
A
F
Q
H
S
T
I
N
S
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
6.6
100
100
100
N.A.
6.6
93.3
6.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
13.3
100
100
100
N.A.
13.3
100
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
0
13
7
0
7
7
7
63
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
63
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
7
0
7
0
0
0
0
0
7
0
7
7
0
0
13
% E
% Phe:
0
0
0
0
13
7
0
0
0
0
7
7
0
13
0
% F
% Gly:
0
0
7
75
0
0
0
0
0
0
0
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
7
7
0
13
13
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
7
0
57
0
% K
% Leu:
75
0
7
0
0
7
0
0
0
0
0
0
0
0
13
% L
% Met:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
7
7
0
0
0
7
7
7
0
0
0
% N
% Pro:
0
0
0
7
7
7
75
0
0
0
7
7
63
0
0
% P
% Gln:
0
0
0
7
0
0
7
0
69
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
7
0
7
0
13
69
0
0
7
0
0
% S
% Thr:
7
63
63
0
0
0
13
63
0
7
0
63
0
0
0
% T
% Val:
0
0
0
7
0
0
0
7
0
0
0
0
13
7
7
% V
% Trp:
0
0
0
0
7
69
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _