KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4A
All Species:
13.33
Human Site:
S264
Identified Species:
22.56
UniProt:
Q13619
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13619
NP_001008895.1
759
87680
S264
P
E
Y
L
N
H
V
S
K
R
L
E
E
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
N418
P
E
Y
L
H
H
V
N
K
R
L
E
E
E
A
Dog
Lupus familis
XP_849542
856
98255
S361
P
E
Y
L
N
H
V
S
K
R
L
E
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
S264
P
E
Y
L
N
H
V
S
K
R
L
E
E
E
A
Rat
Rattus norvegicus
Q9JJ31
780
90872
C281
K
E
T
I
L
A
E
C
Q
G
M
I
K
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515026
756
87763
S261
P
E
Y
L
D
H
V
S
K
R
L
E
E
E
G
Chicken
Gallus gallus
XP_420335
883
101241
N388
P
E
Y
L
H
H
V
N
K
R
L
E
E
E
A
Frog
Xenopus laevis
Q6DE95
768
88933
M273
R
E
L
I
S
K
H
M
K
T
I
V
E
M
E
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
N369
P
E
Y
L
H
H
V
N
K
R
L
E
E
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
E256
T
E
Y
L
K
H
V
E
N
R
L
E
E
E
T
Honey Bee
Apis mellifera
XP_392800
814
93580
D316
P
E
Y
L
A
H
V
D
K
R
L
Q
E
E
N
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
K284
Y
M
Q
N
G
G
V
K
F
M
L
E
H
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
A260
H
E
L
L
V
V
F
A
S
Q
L
L
E
K
E
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
I318
I
T
S
L
Y
A
L
I
R
R
D
F
T
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.5
82.7
N.A.
95.1
26.9
N.A.
89.1
72.7
39.4
73.6
N.A.
29.5
64.7
35.2
N.A.
Protein Similarity:
100
N.A.
76.5
85.2
N.A.
97.2
47.9
N.A.
95.2
79.2
58.9
80.2
N.A.
47.4
77
55.4
N.A.
P-Site Identity:
100
N.A.
80
100
N.A.
93.3
6.6
N.A.
93.3
80
20
80
N.A.
66.6
73.3
20
N.A.
P-Site Similarity:
100
N.A.
93.3
100
N.A.
93.3
33.3
N.A.
100
93.3
40
93.3
N.A.
66.6
80
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.1
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
0
8
0
0
0
0
0
0
29
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
86
0
0
0
0
8
8
0
0
0
65
79
65
15
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
22
% G
% His:
8
0
0
0
22
65
8
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
15
0
0
0
8
0
0
8
8
0
0
8
% I
% Lys:
8
0
0
0
8
8
0
8
65
0
0
0
8
15
8
% K
% Leu:
0
0
15
79
8
0
8
0
0
0
79
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
8
8
0
0
8
0
% M
% Asn:
0
0
0
8
22
0
0
22
8
0
0
0
0
0
15
% N
% Pro:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
72
0
0
0
8
0
% R
% Ser:
0
0
8
0
8
0
0
29
8
0
0
0
0
0
0
% S
% Thr:
8
8
8
0
0
0
0
0
0
8
0
0
8
0
8
% T
% Val:
0
0
0
0
8
8
72
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
65
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _