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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4A
All Species:
29.7
Human Site:
S327
Identified Species:
50.26
UniProt:
Q13619
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13619
NP_001008895.1
759
87680
S327
A
Q
M
Y
Q
L
F
S
R
V
R
G
G
Q
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S481
S
L
L
Y
Q
L
F
S
R
V
R
G
G
V
Q
Dog
Lupus familis
XP_849542
856
98255
S424
T
Q
M
Y
Q
L
F
S
R
V
K
G
G
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
S327
T
Q
M
Y
Q
L
F
S
R
V
K
G
G
Q
H
Rat
Rattus norvegicus
Q9JJ31
780
90872
T335
A
A
A
E
T
I
T
T
D
S
E
K
Y
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515026
756
87763
S324
T
Q
M
Y
H
L
F
S
R
M
K
G
G
Q
Q
Chicken
Gallus gallus
XP_420335
883
101241
S451
S
L
L
Y
Q
L
F
S
R
V
R
G
G
V
Q
Frog
Xenopus laevis
Q6DE95
768
88933
V339
E
G
E
G
K
N
P
V
D
Y
I
Q
G
L
L
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
S432
S
L
L
Y
Q
L
F
S
R
V
R
G
G
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S329
Y
S
L
V
A
L
S
S
K
N
L
T
D
L
K
Honey Bee
Apis mellifera
XP_392800
814
93580
S379
S
L
L
Y
N
L
Y
S
R
V
K
N
G
L
V
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
K342
V
K
N
E
D
L
L
K
N
P
V
N
F
V
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N329
T
A
T
N
Q
V
A
N
T
A
S
V
Q
E
Q
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
L374
A
L
M
T
A
H
S
L
S
P
K
D
Y
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.5
82.7
N.A.
95.1
26.9
N.A.
89.1
72.7
39.4
73.6
N.A.
29.5
64.7
35.2
N.A.
Protein Similarity:
100
N.A.
76.5
85.2
N.A.
97.2
47.9
N.A.
95.2
79.2
58.9
80.2
N.A.
47.4
77
55.4
N.A.
P-Site Identity:
100
N.A.
73.3
86.6
N.A.
80
6.6
N.A.
73.3
73.3
6.6
73.3
N.A.
13.3
40
6.6
N.A.
P-Site Similarity:
100
N.A.
86.6
93.3
N.A.
86.6
26.6
N.A.
86.6
86.6
13.3
86.6
N.A.
33.3
66.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.1
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
8
0
15
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
15
0
0
8
8
0
0
% D
% Glu:
8
0
8
15
0
0
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
50
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
0
0
0
0
0
0
50
65
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
8
0
0
8
0
0
8
8
0
36
8
0
0
15
% K
% Leu:
0
36
36
0
0
72
8
8
0
0
8
0
0
22
8
% L
% Met:
0
0
36
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
8
0
8
8
8
0
15
0
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
15
0
0
0
0
0
% P
% Gln:
0
29
0
0
50
0
0
0
0
0
0
8
8
29
50
% Q
% Arg:
0
0
0
0
0
0
0
0
58
0
29
0
0
0
0
% R
% Ser:
29
8
0
0
0
0
15
65
8
8
8
0
0
0
0
% S
% Thr:
29
0
8
8
8
0
8
8
8
0
0
8
0
0
0
% T
% Val:
8
0
0
8
0
8
0
8
0
50
8
8
0
36
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
58
0
0
8
0
0
8
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _