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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4A
All Species:
35.15
Human Site:
S474
Identified Species:
59.49
UniProt:
Q13619
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13619
NP_001008895.1
759
87680
S474
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S628
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Dog
Lupus familis
XP_849542
856
98255
S571
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
S474
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Rat
Rattus norvegicus
Q9JJ31
780
90872
M476
D
S
E
I
E
E
N
M
V
E
W
L
R
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515026
756
87763
S471
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Chicken
Gallus gallus
XP_420335
883
101241
S598
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Frog
Xenopus laevis
Q6DE95
768
88933
N453
V
S
D
D
S
E
K
N
M
I
S
K
L
K
T
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
S579
A
S
V
D
A
E
K
S
M
L
S
K
L
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
M486
A
S
D
D
A
E
A
M
M
I
S
K
L
K
Q
Honey Bee
Apis mellifera
XP_392800
814
93580
S526
A
S
V
D
A
E
K
S
M
L
S
K
L
K
Q
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
A459
C
S
D
D
V
E
K
A
L
L
A
K
L
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S454
A
N
D
D
H
E
R
S
I
L
T
K
L
K
Q
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
N502
T
S
A
E
D
E
E
N
I
I
Q
R
L
Q
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.5
82.7
N.A.
95.1
26.9
N.A.
89.1
72.7
39.4
73.6
N.A.
29.5
64.7
35.2
N.A.
Protein Similarity:
100
N.A.
76.5
85.2
N.A.
97.2
47.9
N.A.
95.2
79.2
58.9
80.2
N.A.
47.4
77
55.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
100
60
100
N.A.
66.6
93.3
53.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
100
100
80
100
N.A.
73.3
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.1
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
8
0
65
0
8
8
0
0
8
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
29
86
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
8
100
8
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
50
% H
% Ile:
0
0
0
8
0
0
0
0
15
22
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
72
0
0
0
0
86
0
86
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
72
0
8
93
0
0
% L
% Met:
0
0
0
0
0
0
0
15
72
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
22
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% R
% Ser:
0
93
0
0
8
0
0
65
0
0
72
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% T
% Val:
8
0
58
0
8
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _