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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4A
All Species:
28.18
Human Site:
T276
Identified Species:
47.69
UniProt:
Q13619
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13619
NP_001008895.1
759
87680
T276
E
E
G
D
R
V
I
T
Y
L
D
H
S
T
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
T430
E
E
A
D
R
L
I
T
Y
L
D
Q
T
T
Q
Dog
Lupus familis
XP_849542
856
98255
T373
E
E
G
D
R
V
I
T
Y
L
D
H
S
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
T276
E
E
A
D
R
V
I
T
Y
L
D
H
S
T
Q
Rat
Rattus norvegicus
Q9JJ31
780
90872
L293
K
R
N
E
T
E
K
L
H
L
M
F
S
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515026
756
87763
T273
E
E
G
D
R
I
I
T
Y
L
D
Q
S
T
Q
Chicken
Gallus gallus
XP_420335
883
101241
T400
E
E
A
D
R
I
I
T
Y
L
D
Q
S
T
Q
Frog
Xenopus laevis
Q6DE95
768
88933
V285
E
M
E
N
S
G
L
V
H
M
L
K
N
G
K
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
T381
E
E
A
D
R
V
I
T
Y
L
D
Q
S
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
G268
E
E
T
Q
R
V
R
G
F
N
S
K
N
G
L
Honey Bee
Apis mellifera
XP_392800
814
93580
H328
E
E
N
E
R
L
L
H
Y
L
D
A
S
T
K
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
T296
H
K
K
I
E
D
L
T
R
I
F
R
I
F
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
R272
E
K
E
H
S
G
C
R
A
L
L
R
D
D
K
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S330
T
L
I
P
R
M
A
S
V
F
E
N
Y
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.5
82.7
N.A.
95.1
26.9
N.A.
89.1
72.7
39.4
73.6
N.A.
29.5
64.7
35.2
N.A.
Protein Similarity:
100
N.A.
76.5
85.2
N.A.
97.2
47.9
N.A.
95.2
79.2
58.9
80.2
N.A.
47.4
77
55.4
N.A.
P-Site Identity:
100
N.A.
73.3
100
N.A.
93.3
13.3
N.A.
86.6
80
6.6
86.6
N.A.
26.6
53.3
6.6
N.A.
P-Site Similarity:
100
N.A.
86.6
100
N.A.
93.3
33.3
N.A.
93.3
86.6
46.6
86.6
N.A.
40
80
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.1
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
0
0
0
8
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
8
0
0
0
0
58
0
8
8
0
% D
% Glu:
79
65
15
15
8
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
8
8
0
8
0
% F
% Gly:
0
0
22
0
0
15
0
8
0
0
0
0
0
15
0
% G
% His:
8
0
0
8
0
0
0
8
15
0
0
22
0
0
0
% H
% Ile:
0
0
8
8
0
15
50
0
0
8
0
0
8
0
0
% I
% Lys:
8
15
8
0
0
0
8
0
0
0
0
15
0
0
36
% K
% Leu:
0
8
0
0
0
15
22
8
0
72
15
0
0
8
8
% L
% Met:
0
8
0
0
0
8
0
0
0
8
8
0
0
0
8
% M
% Asn:
0
0
15
8
0
0
0
0
0
8
0
8
15
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
29
0
0
50
% Q
% Arg:
0
8
0
0
72
0
8
8
8
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
15
0
0
8
0
0
8
0
58
0
0
% S
% Thr:
8
0
8
0
8
0
0
58
0
0
0
0
8
58
0
% T
% Val:
0
0
0
0
0
36
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
58
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _