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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4A
All Species:
31.21
Human Site:
T59
Identified Species:
52.82
UniProt:
Q13619
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13619
NP_001008895.1
759
87680
T59
P
R
L
P
D
N
Y
T
Q
D
T
W
R
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
T213
P
K
L
P
E
N
Y
T
D
E
T
W
Q
K
L
Dog
Lupus familis
XP_849542
856
98255
T156
P
R
L
P
D
N
Y
T
Q
D
T
W
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
T59
P
R
L
P
D
N
Y
T
Q
D
T
W
R
K
L
Rat
Rattus norvegicus
Q9JJ31
780
90872
H83
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515026
756
87763
T56
P
K
L
P
D
N
Y
T
Q
D
T
W
Q
Q
L
Chicken
Gallus gallus
XP_420335
883
101241
T183
P
K
L
P
E
N
Y
T
D
E
T
W
Q
K
L
Frog
Xenopus laevis
Q6DE95
768
88933
T75
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
T164
P
K
L
P
E
N
Y
T
N
E
T
W
Q
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
A58
D
Y
C
T
S
V
S
A
A
P
S
G
R
S
S
Honey Bee
Apis mellifera
XP_392800
814
93580
Q111
P
K
L
P
E
N
Y
Q
E
Q
T
W
E
K
L
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
M82
K
D
V
I
Q
D
H
M
A
S
V
R
I
R
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S59
Q
K
P
P
H
D
Y
S
Q
Q
L
Y
D
K
Y
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S70
S
R
S
S
G
H
F
S
T
D
S
R
T
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.5
82.7
N.A.
95.1
26.9
N.A.
89.1
72.7
39.4
73.6
N.A.
29.5
64.7
35.2
N.A.
Protein Similarity:
100
N.A.
76.5
85.2
N.A.
97.2
47.9
N.A.
95.2
79.2
58.9
80.2
N.A.
47.4
77
55.4
N.A.
P-Site Identity:
100
N.A.
66.6
93.3
N.A.
100
20
N.A.
80
66.6
13.3
66.6
N.A.
6.6
60
0
N.A.
P-Site Similarity:
100
N.A.
93.3
100
N.A.
100
26.6
N.A.
100
93.3
13.3
93.3
N.A.
13.3
80
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.1
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
15
0
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
29
15
0
0
15
43
8
0
8
0
0
% D
% Glu:
0
0
0
8
29
0
0
0
8
22
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
8
0
0
8
0
8
0
% G
% His:
0
8
0
0
8
8
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
15
43
0
0
8
0
0
0
0
0
0
0
0
58
0
% K
% Leu:
0
0
58
0
0
15
0
0
0
8
8
0
0
8
65
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
58
0
0
8
0
0
0
0
0
0
% N
% Pro:
58
0
8
65
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
8
0
0
8
0
0
8
43
15
0
0
36
8
8
% Q
% Arg:
0
29
0
8
0
0
0
0
0
0
8
15
22
8
0
% R
% Ser:
8
0
8
8
8
0
15
15
0
8
15
0
0
8
8
% S
% Thr:
0
0
0
8
0
0
0
58
8
0
58
8
8
0
8
% T
% Val:
0
0
8
0
8
8
0
0
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% W
% Tyr:
0
8
0
0
0
0
72
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _