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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
10
Human Site:
S143
Identified Species:
16.92
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
S143
E
E
S
S
S
S
S
S
S
S
S
P
T
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S143
E
E
S
S
S
S
S
S
S
S
S
P
T
A
A
Dog
Lupus familis
XP_851906
898
102811
N141
S
Q
Q
Q
Q
L
K
N
K
S
I
L
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
C94
Y
Q
A
V
E
N
L
C
S
H
K
V
S
P
T
Rat
Rattus norvegicus
Q9JJ31
780
90872
E115
P
K
P
F
C
Q
L
E
V
T
L
L
G
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
S140
Q
Q
Q
Q
Q
L
K
S
K
S
L
L
I
S
S
Chicken
Gallus gallus
XP_420335
883
101241
V139
L
L
I
S
S
V
A
V
G
H
H
A
N
G
L
Frog
Xenopus laevis
Q6GPF3
768
88937
Q103
S
L
N
N
N
F
L
Q
T
L
N
Q
A
W
N
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
S138
S
A
G
S
A
T
F
S
N
S
K
P
G
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
R109
G
E
E
V
L
L
S
R
Y
T
K
Q
W
K
S
Honey Bee
Apis mellifera
XP_392800
814
93580
V142
L
E
E
L
Y
Q
A
V
E
N
M
C
N
H
K
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
A112
S
W
A
D
H
T
V
A
M
V
M
I
R
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y73
Y
R
E
A
F
E
E
Y
I
N
S
T
V
L
P
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
W138
F
D
Y
M
N
R
Y
W
V
Q
K
E
R
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
0
N.A.
13.3
13.3
0
40
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
N.A.
100
33.3
N.A.
33.3
13.3
N.A.
40
20
33.3
60
N.A.
26.6
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
8
8
0
15
8
0
0
0
8
8
22
22
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
15
29
22
0
8
8
8
8
8
0
0
8
0
0
0
% E
% Phe:
8
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
8
0
0
0
15
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
15
8
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
8
8
15
0
8
% I
% Lys:
0
8
0
0
0
0
15
0
15
0
29
0
0
15
8
% K
% Leu:
15
15
0
8
8
22
22
0
0
8
15
22
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
8
0
15
0
0
0
0
% M
% Asn:
0
0
8
8
15
8
0
8
8
15
8
0
15
0
8
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
22
0
8
8
% P
% Gln:
8
22
15
15
15
15
0
8
0
8
0
15
0
0
8
% Q
% Arg:
0
8
0
0
0
8
0
8
0
0
0
0
15
0
0
% R
% Ser:
29
0
15
29
22
15
22
29
22
36
22
0
8
22
22
% S
% Thr:
0
0
0
0
0
15
0
0
8
15
0
8
15
0
8
% T
% Val:
0
0
0
15
0
8
8
15
15
8
0
8
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
8
0
0
0
0
8
8
0
% W
% Tyr:
15
0
8
0
8
0
8
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _