KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
9.09
Human Site:
S166
Identified Species:
15.38
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
S166
N
K
S
I
L
I
S
S
V
A
S
V
H
H
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S166
N
K
S
I
L
I
S
S
V
A
S
V
H
H
A
Dog
Lupus familis
XP_851906
898
102811
T164
G
L
A
K
S
S
T
T
T
S
S
F
A
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
Q117
C
E
D
H
V
Q
A
Q
I
L
P
F
R
E
D
Rat
Rattus norvegicus
Q9JJ31
780
90872
L138
E
D
S
I
V
R
K
L
M
L
D
T
W
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
T163
G
L
T
K
T
S
T
T
V
S
S
F
A
N
S
Chicken
Gallus gallus
XP_420335
883
101241
G162
S
F
A
N
S
K
P
G
S
A
K
K
L
V
I
Frog
Xenopus laevis
Q6GPF3
768
88937
M126
I
R
D
I
L
M
Y
M
D
R
V
Y
V
Q
Q
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
E161
K
E
K
P
K
L
P
E
N
Y
T
N
E
T
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N132
D
G
I
C
N
Y
L
N
R
N
W
V
K
R
E
Honey Bee
Apis mellifera
XP_392800
814
93580
H165
L
T
R
L
T
E
A
H
V
Q
A
N
I
E
Q
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
L135
V
A
Q
N
N
H
V
L
P
V
Y
N
L
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
K96
F
M
L
R
E
L
F
K
R
W
S
N
H
K
V
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
W161
N
T
L
C
L
M
T
W
K
E
V
M
F
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
0
13.3
N.A.
13.3
6.6
13.3
0
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
N.A.
100
46.6
N.A.
26.6
33.3
N.A.
53.3
20
26.6
20
N.A.
20
26.6
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
0
15
0
0
22
8
0
15
0
15
% A
% Cys:
8
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
15
0
0
0
0
0
8
0
8
0
0
8
8
% D
% Glu:
8
15
0
0
8
8
0
8
0
8
0
0
8
15
15
% E
% Phe:
8
8
0
0
0
0
8
0
0
0
0
22
8
0
0
% F
% Gly:
15
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
8
0
8
0
0
0
0
22
15
0
% H
% Ile:
8
0
8
29
0
15
0
0
8
0
0
0
8
0
8
% I
% Lys:
8
15
8
15
8
8
8
8
8
0
8
8
8
8
0
% K
% Leu:
8
15
15
8
29
15
8
15
0
15
0
0
15
0
8
% L
% Met:
0
8
0
0
0
15
0
8
8
0
0
8
0
0
0
% M
% Asn:
22
0
0
15
15
0
0
8
8
8
0
29
0
22
0
% N
% Pro:
0
0
0
8
0
0
15
0
8
0
8
0
0
0
8
% P
% Gln:
0
0
8
0
0
8
0
8
0
8
0
0
0
8
15
% Q
% Arg:
0
8
8
8
0
8
0
0
15
8
0
0
8
8
0
% R
% Ser:
8
0
22
0
15
15
15
15
8
15
36
0
0
0
15
% S
% Thr:
0
15
8
0
15
0
22
15
8
0
8
8
0
8
0
% T
% Val:
8
0
0
0
15
0
8
0
29
8
15
22
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
8
0
8
0
8
% W
% Tyr:
0
0
0
0
0
8
8
0
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _