KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
17.88
Human Site:
S305
Identified Species:
30.26
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
S305
R
Q
M
I
M
I
R
S
I
F
L
F
L
D
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S305
R
Q
M
I
M
I
R
S
I
F
L
F
L
D
R
Dog
Lupus familis
XP_851906
898
102811
S290
R
Q
M
I
M
I
R
S
I
F
L
F
L
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
E237
S
F
E
L
K
F
L
E
E
T
N
C
L
Y
A
Rat
Rattus norvegicus
Q9JJ31
780
90872
V258
T
R
R
E
C
N
S
V
E
A
L
M
E
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
S286
R
Q
M
I
M
I
R
S
I
F
L
F
L
D
R
Chicken
Gallus gallus
XP_420335
883
101241
T283
I
F
L
F
L
D
R
T
Y
V
L
Q
N
S
M
Frog
Xenopus laevis
Q6GPF3
768
88937
E246
A
R
I
N
E
E
I
E
R
V
M
H
C
L
D
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
L282
I
W
D
M
G
L
E
L
F
R
F
Y
I
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
L252
T
N
T
V
T
E
Y
L
K
H
V
E
N
R
L
Honey Bee
Apis mellifera
XP_392800
814
93580
K286
Y
Q
D
A
F
E
T
K
F
L
V
A
T
E
R
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
T255
S
R
Y
L
D
K
M
T
E
A
K
I
L
Q
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S216
S
S
W
I
Q
E
D
S
C
P
D
Y
M
L
K
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
A282
T
K
K
P
L
S
M
A
L
N
K
V
L
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
100
13.3
0
0
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
13.3
13.3
N.A.
100
33.3
20
26.6
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
0
15
0
8
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
0
8
8
8
8
% C
% Asp:
0
0
15
0
8
8
8
0
0
0
8
0
0
29
8
% D
% Glu:
0
0
8
8
8
29
8
15
22
0
0
8
8
8
0
% E
% Phe:
0
15
0
8
8
8
0
0
15
29
8
29
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
15
0
8
36
0
29
8
0
29
0
0
8
8
15
0
% I
% Lys:
0
8
8
0
8
8
0
8
8
0
15
0
0
0
8
% K
% Leu:
0
0
8
15
15
8
8
15
8
8
43
0
50
15
8
% L
% Met:
0
0
29
8
29
0
15
0
0
0
8
8
8
0
8
% M
% Asn:
0
8
0
8
0
8
0
0
0
8
8
0
15
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
36
0
0
8
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
29
22
8
0
0
0
36
0
8
8
0
0
0
8
36
% R
% Ser:
22
8
0
0
0
8
8
36
0
0
0
0
0
8
8
% S
% Thr:
22
0
8
0
8
0
8
15
0
8
0
0
8
0
8
% T
% Val:
0
0
0
8
0
0
0
8
0
15
15
8
0
0
8
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
8
0
8
0
0
15
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _