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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
15.15
Human Site:
S366
Identified Species:
25.64
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
S366
N
G
E
A
I
D
R
S
L
L
R
S
L
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S366
N
G
E
A
I
D
R
S
L
L
R
S
L
L
S
Dog
Lupus familis
XP_851906
898
102811
S351
N
G
E
A
I
D
R
S
L
L
R
S
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
Q293
L
I
A
C
V
E
K
Q
L
L
G
E
H
L
T
Rat
Rattus norvegicus
Q9JJ31
780
90872
L314
I
E
P
M
L
K
D
L
E
E
H
I
I
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
S347
N
G
E
A
I
D
R
S
L
L
R
S
L
L
S
Chicken
Gallus gallus
XP_420335
883
101241
R339
A
I
D
R
S
L
L
R
S
L
L
S
M
L
S
Frog
Xenopus laevis
Q6GPF3
768
88937
L302
D
L
A
C
M
Y
K
L
F
S
R
V
P
N
G
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
L341
D
S
F
E
Q
R
F
L
E
E
T
N
R
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N308
I
F
H
T
E
F
Q
N
L
L
N
A
D
R
N
Honey Bee
Apis mellifera
XP_392800
814
93580
V342
K
W
S
L
I
H
T
V
E
K
Q
L
L
S
E
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
V311
R
I
G
D
S
V
T
V
P
G
G
G
L
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
R272
E
K
E
H
S
G
C
R
A
L
L
R
D
D
K
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
T339
F
E
N
Y
V
K
K
T
G
E
N
E
I
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
20
0
N.A.
100
26.6
6.6
6.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
46.6
20
N.A.
100
40
26.6
20
N.A.
40
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
29
0
0
0
0
8
0
0
8
0
0
15
% A
% Cys:
0
0
0
15
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
8
0
29
8
0
0
0
0
0
15
8
0
% D
% Glu:
8
15
36
8
8
8
0
0
22
22
0
15
0
0
8
% E
% Phe:
8
8
8
0
0
8
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
29
8
0
0
8
0
0
8
8
15
8
0
0
8
% G
% His:
0
0
8
8
0
8
0
0
0
0
8
0
8
0
0
% H
% Ile:
15
22
0
0
36
0
0
0
0
0
0
8
15
0
0
% I
% Lys:
8
8
0
0
0
15
22
0
0
8
0
0
0
8
8
% K
% Leu:
8
8
0
8
8
8
8
22
43
58
15
8
43
50
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
29
0
8
0
0
0
0
8
0
0
15
8
0
8
8
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
8
0
8
29
15
0
0
36
8
8
8
0
% R
% Ser:
0
8
8
0
22
0
0
29
8
8
0
36
0
22
43
% S
% Thr:
0
0
0
8
0
0
15
8
0
0
8
0
0
0
8
% T
% Val:
0
0
0
0
15
8
0
15
0
0
0
8
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _