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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
11.21
Human Site:
S81
Identified Species:
18.97
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
S81
E
D
F
D
S
T
S
S
S
S
S
T
P
P
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
S81
E
D
F
D
S
T
S
S
S
S
S
T
P
P
L
Dog
Lupus familis
XP_851906
898
102811
S79
P
R
D
S
A
S
P
S
T
S
S
F
C
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
A32
A
A
L
A
G
G
P
A
K
P
G
G
T
G
G
Rat
Rattus norvegicus
Q9JJ31
780
90872
W53
D
V
H
A
V
C
L
W
D
D
K
G
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
S78
S
P
P
P
K
N
S
S
S
A
A
S
F
A
G
Chicken
Gallus gallus
XP_420335
883
101241
S77
T
T
S
S
C
S
S
S
G
V
A
S
S
N
H
Frog
Xenopus laevis
Q6GPF3
768
88937
I41
W
D
L
L
K
N
A
I
Q
E
I
Q
R
K
N
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
Q76
S
S
Q
Q
Q
Q
Q
Q
Q
H
I
Q
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
T47
S
Q
Y
M
R
F
Y
T
H
V
Y
D
Y
C
T
Honey Bee
Apis mellifera
XP_392800
814
93580
I80
N
P
N
G
V
N
K
I
S
P
S
L
A
S
A
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
S50
R
K
N
N
S
G
L
S
F
E
E
L
Y
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
G11
K
T
I
D
L
E
Q
G
W
D
Y
M
Q
T
G
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
G76
F
S
T
D
S
R
T
G
Q
S
T
I
L
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
20
N.A.
0
0
N.A.
20
13.3
6.6
6.6
N.A.
0
13.3
13.3
N.A.
P-Site Similarity:
100
N.A.
100
40
N.A.
6.6
6.6
N.A.
40
33.3
13.3
6.6
N.A.
13.3
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
8
0
8
8
0
8
15
0
8
8
8
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
8
8
0
% C
% Asp:
8
22
8
29
0
0
0
0
8
15
0
8
0
0
0
% D
% Glu:
15
0
0
0
0
8
0
0
0
15
8
0
0
0
0
% E
% Phe:
8
0
15
0
0
8
0
0
8
0
0
8
8
0
0
% F
% Gly:
0
0
0
8
8
15
0
15
8
0
8
15
0
8
36
% G
% His:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
15
0
0
15
8
0
0
0
% I
% Lys:
8
8
0
0
15
0
8
0
8
0
8
0
8
15
8
% K
% Leu:
0
0
15
8
8
0
15
0
0
0
0
15
8
8
22
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
15
8
0
22
0
0
0
0
0
0
0
8
15
% N
% Pro:
8
15
8
8
0
0
15
0
0
15
0
0
15
15
0
% P
% Gln:
0
8
8
8
8
8
15
8
22
0
0
15
8
0
0
% Q
% Arg:
8
8
0
0
8
8
0
0
0
0
0
0
8
8
0
% R
% Ser:
22
15
8
15
29
15
29
43
29
29
29
15
15
15
0
% S
% Thr:
8
15
8
0
0
15
8
8
8
0
8
15
8
8
8
% T
% Val:
0
8
0
0
15
0
0
0
0
15
0
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
15
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _