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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL4B
All Species:
17.27
Human Site:
Y413
Identified Species:
29.23
UniProt:
Q13620
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13620
NP_001073341.1
895
102299
Y413
Q
E
R
E
V
P
E
Y
L
H
H
V
N
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086195
913
103935
Y413
Q
E
R
E
V
P
E
Y
L
H
H
V
N
K
R
Dog
Lupus familis
XP_851906
898
102811
Y398
Q
E
R
E
V
P
E
Y
L
H
H
V
N
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCH7
759
87735
H339
G
Q
H
A
L
L
Q
H
W
S
E
Y
I
K
T
Rat
Rattus norvegicus
Q9JJ31
780
90872
Q360
K
L
V
K
E
A
F
Q
D
D
P
R
F
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510185
894
102133
Y394
Q
E
R
E
V
P
E
Y
L
H
H
V
N
K
R
Chicken
Gallus gallus
XP_420335
883
101241
H385
R
E
V
P
E
Y
L
H
H
V
N
K
R
L
E
Frog
Xenopus laevis
Q6GPF3
768
88937
L348
Y
I
Q
G
L
L
D
L
K
S
R
F
D
R
F
Zebra Danio
Brachydanio rerio
NP_001116316
864
99408
S390
L
D
Q
S
T
Q
K
S
L
I
A
T
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
C354
G
T
E
A
I
A
K
C
C
T
T
D
A
A
N
Honey Bee
Apis mellifera
XP_392800
814
93580
L388
V
K
N
G
L
V
E
L
C
L
N
F
N
S
Y
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
Y357
E
L
L
Q
L
K
D
Y
F
S
S
L
L
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Q318
E
G
N
A
L
V
Q
Q
A
E
D
T
A
T
N
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
E385
D
Y
I
K
K
L
L
E
V
H
D
I
F
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.2
N.A.
69.7
23.7
N.A.
87.5
88.7
33.1
82.1
N.A.
25.8
61.2
21.7
N.A.
Protein Similarity:
100
N.A.
100
97.4
N.A.
77.1
44.1
N.A.
91.3
92.3
50.3
87.4
N.A.
45.2
75
40.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
6.6
0
N.A.
100
6.6
0
6.6
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
33.3
13.3
N.A.
100
26.6
33.3
40
N.A.
13.3
33.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
0
15
0
0
8
0
8
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
15
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
15
0
8
8
15
8
8
0
0
% D
% Glu:
15
36
8
29
15
0
36
8
0
8
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
0
15
15
0
8
% F
% Gly:
15
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
15
8
36
29
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
0
0
8
0
8
8
0
0
% I
% Lys:
8
8
0
15
8
8
15
0
8
0
0
8
0
36
15
% K
% Leu:
8
15
8
0
36
22
15
15
36
8
0
8
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
15
0
36
0
15
% N
% Pro:
0
0
0
8
0
29
0
0
0
0
8
0
0
0
0
% P
% Gln:
29
8
15
8
0
8
15
15
0
0
0
0
0
0
0
% Q
% Arg:
8
0
29
0
0
0
0
0
0
0
8
8
8
8
29
% R
% Ser:
0
0
0
8
0
0
0
8
0
22
8
0
0
15
0
% S
% Thr:
0
8
0
0
8
0
0
0
0
8
8
15
0
15
22
% T
% Val:
8
0
15
0
29
15
0
0
8
8
0
29
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
8
0
36
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _