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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A1
All Species:
26.67
Human Site:
T688
Identified Species:
65.19
UniProt:
Q13621
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13621
NP_000329.2
1099
121450
T688
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Chimpanzee
Pan troglodytes
NP_001104309
1099
121524
T688
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Rhesus Macaque
Macaca mulatta
XP_001112870
1099
121456
T688
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Dog
Lupus familis
XP_850426
1100
121382
T689
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P55014
1095
120337
T684
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Rat
Rattus norvegicus
P55016
1095
120578
T684
R
P
Q
C
I
V
L
T
G
G
P
M
T
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413814
1097
121884
T686
R
P
Q
C
I
V
L
T
G
A
P
M
I
R
P
Frog
Xenopus laevis
Q0VGW6
899
98326
V525
K
Y
L
L
L
L
D
V
R
K
D
H
V
K
F
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
M525
Q
V
R
K
Y
L
L
M
L
D
S
R
K
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34261
903
100556
D529
Y
L
L
Q
L
K
I
D
K
Q
I
N
D
W
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
96.1
N.A.
93.7
92.2
N.A.
N.A.
82
21.3
23.1
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
100
99.6
99.4
98
N.A.
96.4
95.6
N.A.
N.A.
90.9
39.5
41.2
N.A.
N.A.
N.A.
42.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
26.6
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
10
10
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
70
60
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
70
0
10
0
0
0
10
0
10
0
0
% I
% Lys:
10
0
0
10
0
10
0
0
10
10
0
0
10
10
0
% K
% Leu:
0
10
20
10
20
20
80
0
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
70
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
0
70
0
0
0
70
% P
% Gln:
10
0
70
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
70
0
10
0
0
0
0
0
10
0
0
10
0
70
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
0
0
0
60
0
0
% T
% Val:
0
10
0
0
0
70
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _