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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTCH1
All Species:
4.24
Human Site:
Y49
Identified Species:
10.37
UniProt:
Q13635
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13635
NP_000255.2
1447
160545
Y49
A
A
A
P
D
R
D
Y
L
H
R
P
S
Y
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111868
801
89943
Dog
Lupus familis
XP_539636
1126
122022
Cat
Felis silvestris
Mouse
Mus musculus
Q61115
1434
159255
Q50
D
A
A
F
A
L
E
Q
I
S
K
G
K
A
T
Rat
Rattus norvegicus
NP_446018
1434
159240
Q50
D
A
A
F
A
L
E
Q
I
S
K
G
K
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90693
1442
160559
Y50
A
A
A
P
D
R
E
Y
L
Q
R
P
S
Y
C
Frog
Xenopus laevis
NP_001082082
1418
158209
C46
Y
L
Q
R
P
S
Y
C
D
A
N
F
A
L
Q
Zebra Danio
Brachydanio rerio
Q98864
1220
135526
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18502
1286
142812
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194999
686
77000
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
53
44.7
N.A.
95.4
95.3
N.A.
N.A.
88.2
79.4
54.5
N.A.
36.7
N.A.
N.A.
22.6
Protein Similarity:
100
N.A.
53.5
58.8
N.A.
96.8
96.8
N.A.
N.A.
92.8
85.6
66.9
N.A.
55.3
N.A.
N.A.
32.2
P-Site Identity:
100
N.A.
0
0
N.A.
13.3
13.3
N.A.
N.A.
86.6
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
0
0
N.A.
33.3
33.3
N.A.
N.A.
93.3
6.6
0
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
40
40
0
20
0
0
0
0
10
0
0
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
20
% C
% Asp:
20
0
0
0
20
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
20
0
20
0
0
% K
% Leu:
0
10
0
0
0
20
0
0
20
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
20
10
0
0
0
0
0
0
20
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
20
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
20
0
0
0
0
20
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
20
0
0
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
10
20
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _