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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR4
All Species:
23.33
Human Site:
T255
Identified Species:
42.78
UniProt:
Q13639
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13639
NP_000861.1
388
43761
T255
T
H
R
M
R
T
E
T
K
A
A
K
T
L
C
Chimpanzee
Pan troglodytes
Q5QD29
339
39067
Y211
S
I
M
L
C
V
Y
Y
R
I
Y
L
I
A
K
Rhesus Macaque
Macaca mulatta
Q8HZ64
338
38779
Y210
S
I
M
L
C
I
Y
Y
R
I
Y
L
I
A
K
Dog
Lupus familis
XP_546316
388
43795
T255
T
H
R
M
R
T
E
T
K
A
A
K
T
L
C
Cat
Felis silvestris
Mouse
Mus musculus
P97288
388
43913
T255
T
H
R
M
R
T
E
T
K
A
A
K
T
L
C
Rat
Rattus norvegicus
Q62758
406
46089
T255
T
H
R
M
R
T
E
T
K
A
A
K
T
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507325
355
40204
Q226
A
H
Q
I
R
I
L
Q
R
A
G
A
P
L
D
Chicken
Gallus gallus
XP_414481
410
46746
T278
T
H
R
M
K
T
E
T
K
A
A
K
T
L
C
Frog
Xenopus laevis
P42289
451
50531
S257
L
D
C
Q
Q
P
E
S
S
L
K
T
S
F
K
Zebra Danio
Brachydanio rerio
XP_684857
395
44418
R258
Q
R
I
Y
V
T
A
R
E
H
A
R
Q
I
S
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
T266
K
M
S
F
K
R
E
T
K
V
L
K
T
L
S
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
R346
I
S
T
M
R
R
E
R
K
A
A
R
T
L
G
Honey Bee
Apis mellifera
XP_397139
428
48820
P279
S
A
G
L
A
T
L
P
T
V
D
Q
S
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.1
30.9
95.8
N.A.
93.5
88.1
N.A.
81.1
79.5
33.4
71.3
32.4
31.1
37.3
N.A.
N.A.
Protein Similarity:
100
48.9
49.4
97.1
N.A.
96.3
91.6
N.A.
85.5
85.3
49.2
78.4
49.4
44.4
52.3
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
26.6
93.3
6.6
13.3
40
53.3
6.6
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
46.6
100
26.6
33.3
46.6
60
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
8
0
0
54
54
8
0
16
0
% A
% Cys:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
39
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
16
% D
% Glu:
0
0
0
0
0
0
62
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
47
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
16
8
8
0
16
0
0
0
16
0
0
16
8
0
% I
% Lys:
8
0
0
0
16
0
0
0
54
0
8
47
0
0
24
% K
% Leu:
8
0
0
24
0
0
16
0
0
8
8
16
0
62
0
% L
% Met:
0
8
16
47
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
0
0
8
8
0
% P
% Gln:
8
0
8
8
8
0
0
8
0
0
0
8
8
0
0
% Q
% Arg:
0
8
39
0
47
16
0
16
24
0
0
16
0
0
0
% R
% Ser:
24
8
8
0
0
0
0
8
8
0
0
0
16
0
16
% S
% Thr:
39
0
8
0
0
54
0
47
8
0
0
8
54
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
16
16
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _