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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALKBH1 All Species: 16.97
Human Site: S245 Identified Species: 33.94
UniProt: Q13686 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13686 NP_006011.2 389 43832 S245 D H S K P L L S F S F G Q S A
Chimpanzee Pan troglodytes XP_510096 389 43799 S245 D H S K P L L S F S F G Q S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537525 389 43676 S245 D H S K P L L S F S F G Q S V
Cat Felis silvestris
Mouse Mus musculus P0CB42 389 43728 S245 D H S K P L L S F S F G Q S A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505295 370 41134 R242 F L L G G L K R D E A P T A M
Chicken Gallus gallus NP_001026723 371 41376 G242 Q S S I F L L G G L K R E E A
Frog Xenopus laevis NP_001087992 397 44781 S246 D H Q S P L L S F S F G Q S C
Zebra Danio Brachydanio rerio NP_001018527 363 41327 K241 V F L L G G T K R E D R P T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996458 332 38008 N211 H T D H S E P N K S A P L F S
Honey Bee Apis mellifera XP_392512 310 36363 N189 I I N Y Y R M N S T L A G H T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785154 488 54803 A319 V G D H P A V A L R G A Q K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SA98 345 39002 F224 A M P D G E E F R P E G A I V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87.1 N.A. 82.7 N.A. N.A. 72.4 67 55.9 53.2 N.A. 28.5 32.9 N.A. 32.3
Protein Similarity: 100 100 N.A. 94 N.A. 90.7 N.A. N.A. 80.9 77.8 68.7 69.4 N.A. 48.3 48.3 N.A. 48.1
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 N.A. N.A. 6.6 26.6 80 6.6 N.A. 6.6 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 N.A. N.A. 13.3 33.3 80 13.3 N.A. 20 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 9 0 0 17 17 9 9 42 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 42 0 17 9 0 0 0 0 9 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 17 9 0 0 17 9 0 9 9 0 % E
% Phe: 9 9 0 0 9 0 0 9 42 0 42 0 0 9 0 % F
% Gly: 0 9 0 9 25 9 0 9 9 0 9 50 9 0 9 % G
% His: 9 42 0 17 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 9 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 34 0 0 9 9 9 0 9 0 0 9 0 % K
% Leu: 0 9 17 9 0 59 50 0 9 9 9 0 9 0 0 % L
% Met: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 50 0 9 0 0 9 0 17 9 0 0 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 0 0 50 0 0 % Q
% Arg: 0 0 0 0 0 9 0 9 17 9 0 17 0 0 0 % R
% Ser: 0 9 42 9 9 0 0 42 9 50 0 0 0 42 9 % S
% Thr: 0 9 0 0 0 0 9 0 0 9 0 0 9 9 9 % T
% Val: 17 0 0 0 0 0 9 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _