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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALKBH1 All Species: 16.67
Human Site: S378 Identified Species: 33.33
UniProt: Q13686 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13686 NP_006011.2 389 43832 S378 C H L D D Q N S E V K R A R I
Chimpanzee Pan troglodytes XP_510096 389 43799 S378 C H L D D Q N S E V K R A R I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537525 389 43676 S378 C H L D D D S S Q V K R M K L
Cat Felis silvestris
Mouse Mus musculus P0CB42 389 43728 S378 C H L H D P N S P V K R K R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505295 370 41134 G359 C R L D D E S G Q V K R P K R
Chicken Gallus gallus NP_001026723 371 41376 S361 D S H H Q E N S R A K R H K P
Frog Xenopus laevis NP_001087992 397 44781 V386 E G L D A K G V L M K R M K M
Zebra Danio Brachydanio rerio NP_001018527 363 41327 R353 E P Q M I K K R K S E S G Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996458 332 38008 R322 S R I N I N I R Q V L N P G D
Honey Bee Apis mellifera XP_392512 310 36363 Q300 R I N M N V R Q V L K V G Q F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785154 488 54803 S478 D R D M V Q S S N T K R I K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SA98 345 39002 S335 F A E Y I K T S R I N I N I R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87.1 N.A. 82.7 N.A. N.A. 72.4 67 55.9 53.2 N.A. 28.5 32.9 N.A. 32.3
Protein Similarity: 100 100 N.A. 94 N.A. 90.7 N.A. N.A. 80.9 77.8 68.7 69.4 N.A. 48.3 48.3 N.A. 48.1
P-Site Identity: 100 100 N.A. 60 N.A. 66.6 N.A. N.A. 46.6 26.6 26.6 0 N.A. 6.6 6.6 N.A. 33.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. 73.3 N.A. N.A. 73.3 40 53.3 20 N.A. 26.6 26.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 23.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 0 0 0 9 0 0 17 0 0 % A
% Cys: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 9 42 42 9 0 0 0 0 0 0 0 0 9 % D
% Glu: 17 0 9 0 0 17 0 0 17 0 9 0 0 0 9 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 9 0 0 0 0 9 9 0 0 0 0 17 9 0 % G
% His: 0 34 9 17 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 9 0 25 0 9 0 0 9 0 9 9 9 25 % I
% Lys: 0 0 0 0 0 25 9 0 9 0 75 0 9 42 0 % K
% Leu: 0 0 50 0 0 0 0 0 9 9 9 0 0 0 17 % L
% Met: 0 0 0 25 0 0 0 0 0 9 0 0 17 0 9 % M
% Asn: 0 0 9 9 9 9 34 0 9 0 9 9 9 0 0 % N
% Pro: 0 9 0 0 0 9 0 0 9 0 0 0 17 0 9 % P
% Gln: 0 0 9 0 9 25 0 9 25 0 0 0 0 9 0 % Q
% Arg: 9 25 0 0 0 0 9 17 17 0 0 67 0 25 17 % R
% Ser: 9 9 0 0 0 0 25 59 0 9 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 9 9 0 9 9 50 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _