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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1S All Species: 25.15
Human Site: Y1101 Identified Species: 79.05
UniProt: Q13698 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13698 NP_000060.2 1873 212350 Y1101 K A R P L R C Y I P K N P Y Q
Chimpanzee Pan troglodytes XP_525018 1874 212521 Y1102 K A R P L R C Y I P K N P Y Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848685 1876 212961 Y1104 K A R P L R C Y I P K N P Y Q
Cat Felis silvestris
Mouse Mus musculus Q02789 1880 213241 Y1101 K A R P L R C Y I P K N P Y Q
Rat Rattus norvegicus P22002 2169 243464 Y1231 K A R P L P R Y I P K N Q H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 Y1209 K A R P L R R Y I P K N P Y Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139622 1777 202411 G1074 F M M N I F V G F V I V T F Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24270 2516 276682 Y1646 K A K P V R R Y I P K H G I Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 91.5 N.A. 90.9 58 N.A. N.A. 56.8 N.A. 67.8 N.A. 40.5 N.A. N.A. N.A.
Protein Similarity: 100 98.8 N.A. 94.9 N.A. 94.7 69.6 N.A. N.A. 68.5 N.A. 78.9 N.A. 52.5 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 73.3 N.A. N.A. 93.3 N.A. 6.6 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 80 N.A. N.A. 93.3 N.A. 20 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 13 0 0 0 0 13 0 0 13 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 13 0 13 0 % H
% Ile: 0 0 0 0 13 0 0 0 88 0 13 0 0 13 0 % I
% Lys: 88 0 13 0 0 0 0 0 0 0 88 0 0 0 0 % K
% Leu: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 75 0 0 0 % N
% Pro: 0 0 0 88 0 13 0 0 0 88 0 0 63 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 100 % Q
% Arg: 0 0 75 0 0 75 38 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % T
% Val: 0 0 0 0 13 0 13 0 0 13 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 88 0 0 0 0 0 63 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _